Mucolipin 3 (Mcoln3) (N-Term) Antikörper

Antigen: Mucolipin 3 (Mcoln3)

Synonyme: Va, TRPML3, MGC124245, MGC124246, 6720490O21Rik, TRP-ML3, FLJ11006, FLJ36629, MGC71509, MGC80434, MCOLN3

Epitope: N-Term

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Maus, Ratte (Rattus)

Applikation: Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN350002

Produktbeschreibung

Weitere Bezeichnung: Mucolipin 3 (Mcoln3, MCLN3,TRPML3) (n-terminal)

Swiss-Prot: Q8R4F0

Immunogen: A synthetic peptide from the n-terminal of mouse, rat Mucolipin 3 (Mcoln3, MCLN3, TRPML3) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Beschreibung: SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in the cochlea; particularly in the inner and outer hair cells. DISEASE: Defects in Mcoln3 are the cause of the varitin-waddler (Va) phenotype. Classical Va mice exhibit early-onset hearing loss, vestibular defects, pigmentation abnormalities and perinatal lethality. The phenotype varitin-waddler Jackcon (Va-J), which arose in a cross segregating for Va, is similar but less severe. Also known as: MCLN3, Mcoln3Mucolipin 3, Va, TRPML3, TRP-ML3.

Spezifität: Appears to be specific for Mucolipin 3.

Anwendungen

Applikationshinweise: IHC, WB. A dilution of 1: 300 to 1: 3000 is recommended. The optimal dilution should be determined by the end user.

Reinheit: whole serum

Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Gregory, Barlow, McLay et al.: "The DNA sequence and biological annotation of human chromosome 1." in: Nature, Vol. 441, Issue 7091, pp. 315-21, 2006 (PubMed).