Fas Ligand (TNF Superfamily, Member 6) (FASL) Antikörper

Antigen: Fas Ligand (TNF Superfamily, Member 6) (FASL)

Synonyme: FASL, CD178, CD95L, TNFSF6, APT1LG1, gld, Fas-L, Faslg, Tnfsf6, Fas-Ligand, FASLG, fasl, APT1, CD95, FAS1, APO-1, FASTM, ALPS1A, TNFRSF6, lpr, APO1, TNFR6, Tnfrsf6, AI196731, Fasl, CD95-L, Apt1Lg1, FAS, LOC574159, zgc:162027

Klonalität: Monoklonal (ALF1-2)

Wirt: Maus

Reaktivität: Human

Applikation: Durchflusszytometrie (FACS), ELISA

Produktnummer: ABIN348112

Produktbeschreibung

Weitere Bezeichnung: Fas Ligand

Immunogen: Recombinant soluble, active form of human Fas ligand .

Isotyp: IgG1

Klon: ALF1-2

Beschreibung: Fas ligand (FasL), also known as CD95L, is a member of the TNF family and induces apoptosis via binding to Fas (CD95). The protein exists in two forms, either membrane FasL or soluble FasL, which migrate at molecular weight of 45 kDa and 26 kDa, respectively. FasL is expressed on a variety of cells including activated lymphocytes, natural killer cells and monocytes. Interaction of FasL and Fas plays an important role in physiological apoptotic processes. Malfunction of the Fas-FasL system causes hyperplasia in peripheral lymphoid organs and accelerates autoimmune disease progression and tumorigenesis. ALF1.2 antibody reacts with FasL-transfected cells and recognizes soluble and membrane bound forms of human FasL.

Synonyme: FASL, CD178, CD95L, TNFSF6, APT1LG1, gld, Fas-L, Faslg, Tnfsf6, Fas-Ligand, FASLG, fasl, APT1, CD95, FAS1, APO-1, FASTM, ALPS1A, TNFRSF6, lpr, APO1, TNFR6, Tnfrsf6, AI196731, Fasl, CD95-L, Apt1Lg1, FAS, LOC574159, zgc:162027

Anwendungen

Applikationshinweise: This antibody is suitable for use in ELISA and flow cytometry.

Buffer: 0.1% sodium azide (Caution: sodium azide is a poisonous and hazardous substance. Handle with care and dispose of properly.) Purified from ascites by Protein A/G chromatography.

Forschungsgebiet: CD Antigene, Oberflächenrezeptoren der Immunzellen , Apoptose/Nekrose, Virologie, Krebs

Beschränkungen: Nur für Forschungszwecke einsetzbar