AGR3 Antikörper
| Antigen |
|
| Klonalität |
Monoklonal (AGR3-2) |
|
Wirt
|
|
|
Reaktivität
|
|
|
Applikation
|
 Alternativen Western Blot (WB), Immunhistochemie (Gefrierschnitte) (IHC (fro)), Immunzytochemie (ICC)
|
| Produktnummer |
ABIN343712 |
| Menge |
0.1 mg (1 mg/ml) |
| Preis |
290,00 € Zzgl. Versandkosten €20,00 und MWSt
|
| Lieferung nach |
|
| Verfügbarkeit |
Lieferbar innerhalb von 3 bis 5 Werktagen |
|
Immunogen
|
Purified human AGR3 protein
|
|
Format
|
Purified
|
|
Isotyp
|
IgG1 (Passende Sekundärantikörper)
|
|
Klon
|
AGR3-2
|
|
Beschreibung
|
AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG-3, HAG3 in human), orBCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction andp53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutictarget for hormone-responsive breast tumours. Its Xenopus homolog is associated withanteroposterior fate determination during early development.
|
|
Spezifität
|
The antibody AGR3.2 recognizes epitope QYSQALKKV within AGR3 (AG3) protein (19-20kDa), secreted cytoplasmic protein which can serve as a marker of carcinogenesis.
|
|
Applikationshinweise
|
Western Blotting - Recommended dilution: 1 µg/ml. Positive control: T47D breast cancer cell line. Negative control: H1299 lung carcinoma cell line. Immunohistochemistry (frozen sections) - Recommended dilution: 1 µg/ml. Positive tissue: breast cancer. Immunocytochemistry - Recommended dilution: 1 µg/ml. Positive control: T47D breast cancer cell line. Negative control: H1299 lung carcinoma cell line
|
|
Konzentration
|
1 mg/ml
|
|
Reinheit
|
> 95% (by SDS-PAGE)
|
|
Reinigung
|
Purified from ascites by protein-A affinity chromatography.
|
|
Buffer
|
The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azideand 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
|
|
Lagerung
|
Store at 2-8 o C. Do not use after expiration date stamped on vial label. For long-term storage aliquot and store at -20 o C. Avoid freeze/thaw cycles.
|
|
Beschränkungen
|
Nur für Forschungszwecke einsetzbar
|
Alternativen zu Antigen "AGR3", Typ "Antikörper" finden
|
Wirte
|
Maus (5), Kaninchen (4)
|
|
Reaktivitäten
|
Human (9), Maus (1)
|
|
Applikationen
|
Western Blot (WB) (7), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (5), Immunhistochemie (Paraffinschnitte) (IHC (p)) (4), Immunzytochemie (ICC) (3), Durchflusszytometrie (FACS) (2), Immunfluoreszenz (IF) (2), Immunhistochemie (IHC) (2), ELISA (1), ELISA (Detektionsantikörper) (1)
|
