Insulin (INS) Antikörper

Antigen: Insulin (INS)

Synonyme: ILPR, IRDN, INS, MGC159719, ins1, xins, ins1-a, Insulin

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: ELISA

Produktnummer: ABIN343666

Produktbeschreibung

Weitere Bezeichnung: Insulin B chain

Swiss-Prot: P01308

Immunogen: This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to human insulin B chain.

Format: Liquid

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Insulin is a hormone with extensive effects on both metabolism and several other body systems. It causes most of the body's cells to take up glucose from the blood (including liver, muscle, and fat tissue cells), storing it as glycogen in the liver and muscle, and stops use of fat as an energy source. Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to its secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. References: 1. Bell G.I., Pictet R.L., Rutter W.J., Cordell B., Tischer E., Goodman H.M.,Sequence of the human insulin gene.,Nature 284:26-32(1980). 2. Nicol D.S.H.W., Smith L.F.,Amino-acid sequence of human insulin.,Nature 187:483-485(1960). 3. Chang X., Joergensen A.M., Bardrum P., Led J.J.,Solution structures of the R6 human insulin hexamer., Biochemistry 36:9409-9422(1997).

Anwendungen

Applikationshinweise: Dilution: ELISA 1:5000 Molecular Wt. 12kDa SwissProt P01308

Konzentration: 0.53mg/ml

Reinigung: Immunogen affinity purified

Buffer: 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.

Lagerung: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar