L1 Cell Adhesion Molecule (L1CAM) Antikörper

Antigen: L1 Cell Adhesion Molecule (L1CAM)

Synonyme: S10, HSAS, MASA, MIC5, SPG1, CAML1, CD171, HSAS1, N-CAML1, l1cam-a, MGC80658

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Maus, Ratte (Rattus), Human

Applikation: Western Blot (WB), Immunzytochemie (ICC)

Produktnummer: ABIN343658

Produktbeschreibung

Weitere Bezeichnung: NCAML1

Swiss-Prot: P32004/P11627

Immunogen: This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of C-terminal residues of NCAM-L1.

Format: Liquid

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: The neural cell adhesion molecule L1 (NCAM-L1) is an immunoglobulin superfamily adhesion molecule that is critical for neural development, involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Defects in L1CAM are the cause of hydrocephalus due to stenosis of the aqueduct of Sylvius (HSAS). Hydrocephalus is a condition in which abnormal accumulation of cerebrospinal fluid in the brain causes increased intracranial pressure inside the skull. Defects in L1CAM are also the cause of mental retardation, aphasia, shuffling gait, and adducted thumbs syndrome (MASA), a X-linked disorder.

Anwendungen

Applikationshinweise: Dilution: WB: 1:500-1,1000. Positive Control: Fetal brain. Cellular Localization: Cell Membrane. Molecular Weight: ~220kDa.

Konzentration: 0.62mg/ml

Reinigung: Immunogen affinity purified

Buffer: 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.

Lagerung: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blot analysis on fetal brain using anti-NCAML1 polyclonal antibody NCAM-L1