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CD34 (CD34) Antikörper

Antigen

CD34 (CD34)

Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Maus, Human, Ratte (Rattus)

Applikation
Alternativen Western Blot (WB)
Produktnummer ABIN343619
Menge 100ul  (0.5mg/ml)  (Varianten)
Preis 269,23 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Weitere Bezeichnung CD34
Swiss-Prot P28906
Immunogen This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to near C-terminal residues of CD34.
Format Liquid
Isotyp IgG  (Passende Sekundärantikörper)
Beschreibung CD34 is a heavily glycosylated type I transmembrane molecule, that can be phoshorylated by a variety of kinases including Protein kinase C and Tyrosine kinases. CD34 antigen is expressed on small vessel endothelial cells and tumors of epithelial origin. CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. So CD34 is considered to be ideal marker for identifying and quantifying hematopoietic progenitor stem cells. With interaction with CrkL, CD34 becomes a substrate for PKC and CD34 surface expression is associated with activation of PKC.

Anwendungen

Applikationshinweise Dilution: WB: 1:5,000 ICC: 1:250. Positive Control: Mouse Brain Cell. Cellular Localization: Membrane. Molecular Weight: ~90/150kDa + -.
Konzentration 0.5mg/ml
Reinigung Immunogen affinity purified
Buffer 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
Lagerung Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Forschungsgebiet Hämopoetische Vorläufer, Hämatopoetische Stammzellen, Kardiogenese, Abstammungsmarker, CD Antigene, Oberflächenrezeptoren der Immunzellen
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "CD34 (CD34)", Typ "Antikörper" finden
Wirte Maus (171), Ratte (84), Kaninchen (59), Hamster (8), Huhn (4)
Reaktivitäten Human (214), Maus (128), Ratte (Rattus) (33), Hund (28), Rind (Kuh) (15), Schwein (15), Kaninchen (15), Affe (7), Primate (5), Primaten (3), Rhesusaffen (2)
Applikationen Durchflusszytometrie (FACS) (250), Western Blot (WB) (107), Immunhistochemie (Paraffinschnitte) (IHC (p)) (70), Immunfluoreszenz (IF) (56), Immunpräzipitation (IP) (50), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (47), ELISA (29), Immunhistochemie (IHC) (16), Immunzytochemie (ICC) (12), Enzyme Immunoassay (EIA) (8), Funktionale Studien (Func) (8), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (4), Dot Blot (Dot) (2), Immunoelectron Microscopy (IEM) (2)
Konjugate FITC (43), PE (30), Biotin (25), APC (10), Alexa Fluor 647 (8), RPE (6), PE,Cy5 (4), PerCP,Cy5.5 (4), Alexa Fluor 488 (3), Alexa Flour 488 (2), Alexa Fluor 350 (2), Alexa Fluor 555 (2), Alexa Fluor 700 (2), Cy3 (2), Cy5 (2), Cy5,PE (2), Cy5.5 (2), Cy7 (2), Cy7,PE (2), Gold (2), HRP (2), PE,Cy3 (2), PE,Cy5.5 (2), PE,Cy7 (2), RBITC (2), Cy5.5,PE (1), PE,DY647 (1), PE-Dyomics 647 (1), Pacific Blue (1)
Epitope AA 32-290 (1), pTyr330 (1)