Cathepsin D (CTSD) Antikörper

Antigen: Cathepsin D (CTSD)

Synonyme: CPSD, CLN10, MGC2311, CD, CatD, catD, fb93e11, fj17b09, wu:fb93e11, wu:fj17b09, CTSD, LOC398557, Cathd, LOC100136761, DKFZp469J0315

Klonalität: Monoklonal (CP-D13)

Wirt: Bitte anfragen

Reaktivität: Human

Applikation: Western Blot (WB), Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN343604

Produktbeschreibung

Weitere Bezeichnung: Cathepsin D

Immunogen: Human liver cathepsin D. Purification Purified by the goat anti-mouse IgG affinity chromatography.

Format: Affinity-purified

Isotyp: IgG2a

Klon: CP-D13

Beschreibung: Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Cathepsin D is mapped to chromosome 11. The amino acid sequence predicted from the cDNA sequence shows that human cathepsin D consists of 412 amino acids with 20 and 44 amino acids in a pre- and a prosegment, respectively

Spezifität: Human. No cross reactivity with other proteins.

Anwendungen

Applikationshinweise: Western blotting: At 0.5-1 µg/ml with the appropriate system to detect cathepsin D in cells and tissues. Immunohistochemistry (Paraffin-embedded Sections): At 1-2 µg/ml to detect cathepsin D in formalin fixed and paraffin embedded tissues. Other applications have not been tested. Optimal dilutions should be determined by end user.

Buffer: Lyophilized from 1.2% sodium acetate, with 2mg BSA and 0.2mg NaN3 as preservative.

Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100µg/ml.

Forschungsgebiet: Proteolyse / Ubiquitin, Extrazelluläre Matrix, Proteasen, Signaltransduktion

Beschränkungen: Nur für Forschungszwecke einsetzbar