Cdk7/CAK Antikörper

Antigen: Cdk7/CAK

Klonalität: Monoklonal (IMD-26)

Wirt: Bitte anfragen

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN343595

Produktbeschreibung

Immunogen: Recombinant human Cdk7 protein. Purification Purified by the goat anti-mouse IgG affinity chromatography.

Format: Affinity-purified

Isotyp: IgG2b

Klon: IMD-26

Beschreibung: CDK-activating kinases (CAKs) are multisubunit proteins that phosphorylate and thus activate certain cyclin-dependent protein kinases in the regulation of cell cycle progression. Cyclin dependent kinase7( CDK7) gene is mapped to chromosome 2p15-cen. CDK7 functions in both cyclin binding and T-loop phosphorylation and that these 2 steps of CDK1 activation are mutually dependent.

Spezifität: Human. No cross reactivity with other proteins.

Anwendungen

Applikationshinweise: Western blotting: At 0.25 µg/ml with the appropriate system to detect cdk7/cak in cells and tissues. Immunohistochemistry(F) At 0.5 µg/ml to detect cdk7/cak in formalin/acetone fixed tissues. Immunocytochemistry Suitable Other applications have not been tested. Optimal dilutions should be determined by end user.

Buffer: Lyophilized from 1.2% sodium acetate, with 2mg BSA and 0.2mg NaN3 as preservative.

Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100µg/ml.

Beschränkungen: Nur für Forschungszwecke einsetzbar