Elastin (ELN) Antikörper

Antigen: Elastin (ELN)

Synonyme: ELN, MGC148808, WS, WBS, SVAS, FLJ38671, FLJ43523, AI385707, AI480567, E030024M20Rik, Trela, TREL11, Trela26, RATTREL11

Klonalität: Monoklonal (IL-4)

Wirt: Bitte anfragen

Reaktivität: Human, Hund, Meerschweinchen

Applikation: Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN343579

Produktbeschreibung

Weitere Bezeichnung: Elastin

Immunogen: Bovine a-elastin Purification Purified by the goat anti-mouse IgG affinity chromatography.

Format: Affinity-purified

Isotyp: IgG1

Klon: IL-4

Beschreibung: Elastin is a major structural protein of tissues such as aorta, which must expand rapidly and recover completely. Elastin chains are cross-linked together into an extensible 3D network. It is a molecular determinant of late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle. Defects in elastin are a cause of autosomal dominant cutis laxa.

Spezifität: Human, dog, guinea pig. No cross reactivity with other proteins.

Anwendungen

Applikationshinweise: Immunohistochemistry (Paraffin-embedded Sections): At 0.25-0.5 µg/ml to detect elastin in formalin fixed and paraffin embedded tissues. Other applications have not been tested. Optimal dilutions should be determined by end user.

Buffer: Lyophilized from 1.2% sodium acetate, with 2mg BSA and 0.2mg NaN3 as preservative.

Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100µg/ml.

Forschungsgebiet: Kardiovaskuläres System, Extrazelluläre Matrix

Beschränkungen: Nur für Forschungszwecke einsetzbar