Vascular Endothelial Growth Factor (VEGF) Antikörper

Antigen: Vascular Endothelial Growth Factor (VEGF)

Synonyme: vegf-A, VEGF, DmVEGF-1, EP1624, PVF, PVF1, PVFs, VEGF2-B, Vegf17E, Vegf17e-a, Vegf17e-b, l(1)G0146, vegf1, DmelCG7103, CG7103, DmVEGF-2, PV2, PVF2, VEGF-2, VEGF27Cb, DmelCG13780, CG13780, CG13781, CG13782, CG13783, CG31629, CG4492, DmVEGF-3, PVF3, VEGF27Ca, DmelCG34378, CG34378, vegf, LOC100033839

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB), Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN343427

Produktbeschreibung

Weitere Bezeichnung: Vascuoar endothelial growth factor, VEGF

Immunogen: A synthetic peptide corresponding to a sequence near the N-teminal end of VEGF of human origin, identical to the related rat sequences.

Format: Affinity-purified

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: VEGF, a homodimeric glycoprotein of relative molecular mass 45,000, is the only mitogen that specifically acts on endothelial cells. It may be a major regulator of tumor angiogenesis in vivo. Vascular endothelial growth factor is a mitogen primarily for vascular endothelial cells. It is, however, structurally related to platelet-derived growth factor. VEGF shares homology with the PDGF A chain and B chain, including conservation of all 8 cysteines found in PDGFA and PDGFB. VEGF gene contains 8 exons. Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism. Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo.

Spezifität: Human, mouse, rat. No cross reactivity with other proteins.

Synonyme: vegf-A, VEGF, DmVEGF-1, EP1624, PVF, PVF1, PVFs, VEGF2-B, Vegf17E, Vegf17e-a, Vegf17e-b, l(1)G0146, vegf1, DmelCG7103, CG7103, DmVEGF-2, PV2, PVF2, VEGF-2, VEGF27Cb, DmelCG13780, CG13780, CG13781, CG13782, CG13783, CG31629, CG4492, DmVEGF-3, PVF3, VEGF27Ca, DmelCG34378, CG34378, vegf, LOC100033839

Anwendungen

Applikationshinweise: Western blotting: At 0.5-1u/ml with the appropriate system to detect VEGF in cells and tissues. Immunohistochemistry (Paraffin-embedded Sections): At 1-2u/ml to detect VEGF in formalin fixed and paraffin embedded tissues. Boiling the sections is required. Other applications have not been tested. Optimal dilutions should be determined by end user.

Reinheit: Immunogen affinity purified.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .

Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blot analysis ofRat cardiac muscle tissue lysis using VEGF antibody

Immunohistochemical analysis of paraffin-embedded ESCC sections. Staining VEGF in cytoplasmDAB chromogenic reaction