RAD51 Homolog Protein (RAD51) Antikörper

Antigen: RAD51 Homolog Protein (RAD51)

Synonyme: RECA, BRCC5, HRAD51, RAD51A, HsRad51, HsT16930, RAD51, CRAD51, MGC128559, CG7948, D37788, Dm Rad51, DmelCG7948, DMR, DMR/DroRAD51, DMR1, dmRAD51, Dmrad51, DmRad51, DmRAD51, RA51, rad51, Rad51, Rad51dm, Spn-A, spnA, MGC52570, MGC130792, zgc:77754, wu:fb38e12, RGD1563603, GB17143, spn-A, F22D1.20, F22D1_20, MUT5

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB), Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN343380

Produktbeschreibung

Weitere Bezeichnung: DNA repair protein RAD51 homolog 1, RAD51A

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human RAD51A, different from the related rat sequence by one amino acid.

Format: Affinity-purified

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: DNA repair protein RAD51 homolog 1, also known as RAD51A, is a human gene. The Rad51 gene, HsRAD51, is a homolog of RecA of Escherichia coli and functions in recombination and DNA repair. BRCA1 and BRCA2 proteins form a complex with Rad51, and these genes are thought to participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. 1 RAD51 is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. 2

Spezifität: Human, mouse, rat. No cross reactivity with other proteins.

Synonyme: RECA, BRCC5, HRAD51, RAD51A, HsRad51, HsT16930, RAD51, CRAD51, MGC128559, CG7948, D37788, Dm Rad51, DmelCG7948, DMR, DMR/DroRAD51, DMR1, dmRAD51, Dmrad51, DmRad51, DmRAD51, RA51, rad51, Rad51, Rad51dm, Spn-A, spnA, MGC52570, MGC130792, zgc:77754, wu:fb38e12, RGD1563603, GB17143, spn-A, F22D1.20, F22D1_20, MUT5

Anwendungen

Applikationshinweise: WB 1ug/ml (Hu, Rat, Ms). IHC-P 1-2ug/ml (Hu, Rat, Ms). Antigen Retrieval by heat

Reinheit: Immunogen affinity purified.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .

Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml.

Beschränkungen: Nur für Forschungszwecke einsetzbar