Dopamine Receptor D1 (DRD1) Antikörper

Antigen: Dopamine Receptor D1 (DRD1)

Synonyme: D1R, Dop1, D1A, DRD1, DADR, DRD1A, drd1

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Ratte (Rattus), Maus

Applikation: Western Blot (WB)

Produktnummer: ABIN343369

Produktbeschreibung

Weitere Bezeichnung: Dopamine receptor D 1 , DRD1

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human DRD1, identical to the related rat and mouse sequence.

Format: Affinity-purified

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Dopamine receptor D 1 , also known as DRD1, is a human gene. It is the most highly expressed DA receptor subtype among the DA receptor family. 1 Receptors for dopamine have been classified into two functional types, D1 and D2. They belong to the family of receptors acting through G (or guanine nucleotide-binding) proteins. D2 receptors inhibit adenylyl cyclase, but D1 receptors stimulate adenylyl cyclase and activate cyclic AMP-dependent protein kinases. Dopamine D1 and D2 receptors are targets of drug therapy in many psychomotor disorders, including Parkinson's disease and schizophrenia, and may also have a role in drug addiction and alcoholism. D1 receptors regulate neuron growth and differentiation, influence behaviour and modify dopamine D2 receptor-mediated events. And the presence of a D1 receptor gene restriction fragment length polymorphism will be helpful for future disease linkage studies. 2 DRD1 also regulates the neurochemical architecture of the striatum and is critical for the normal expression of motor activity. 3

Spezifität: Human, rat, mouse No cross reactivity with other proteins.

Anwendungen

Applikationshinweise: WB 1ug/ml (Hu, Rat, Ms)

Reinheit: Immunogen affinity purified.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .

Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml.

Beschränkungen: Nur für Forschungszwecke einsetzbar