Keratin 8 (KRT8) Antikörper

Antigen: Keratin 8 (KRT8)

Synonyme: K8, KO, CK8, CYK8, K2C8, CARD2, Card2, EndoA, Krt2-8, Krt-2.8, AA960620, AL022697, AU019895, MGC118110, CYKER, KRT2-8, krt8, MGC53564, KRT8, ck8, cyk8, k2c8, card2, krt2-5, MGC69490, cb59, zf-K8, MGC76893, wu:fa91a11, wu:fd19e09, wu:fl23c09, etID20321.6, zfk8, DreK8, cb186, krt2-8, MGC85764, sb:cb186, MGC174782, wu:fa20h05, wu:fa95h10, wu:fb96c06, DKFZp468F2127

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB), Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN343360

Produktbeschreibung

Weitere Bezeichnung: Cytokeratin 8, CK8

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human CK8, different to the related rat sequence by a single amino acid.

Format: Affinity-purified

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Cytokeratin 8 (CK8), also known as Keratin 8 (K8), is a type II keratin. Among the various intermediate filament (IF) proteins, cytokeratin 8 (CK8) is especially remarkable as it is produced early in embryogenesis, is the only type-II CK occurring in many simple epithelial cells, and can also be synthesized in certain non-epithelial cells. 1 Cytokeratin 8 mRNA was abundant in fetal small intestine, placenta, pancreas, lung, liver, and kidney. Levels of cytokeratin 8 mRNA in placenta increased slightly during pregnancy. 2 He et al. (2002) presented evidence that K8 is a new cytoplasmic target for JNK in Fas receptor-mediated signaling. The functional significance of this phosphorylation could relate to regulation of JNK signaling and/or regulation of keratin dynamics. 3

Spezifität: Human. No cross reactivity with other proteins.

Synonyme: K8, KO, CK8, CYK8, K2C8, CARD2, Card2, EndoA, Krt2-8, Krt-2.8, AA960620, AL022697, AU019895, MGC118110, CYKER, KRT2-8, krt8, MGC53564, KRT8, ck8, cyk8, k2c8, card2, krt2-5, MGC69490, cb59, zf-K8, MGC76893, wu:fa91a11, wu:fd19e09, wu:fl23c09, etID20321.6, zfk8, DreK8, cb186, krt2-8, MGC85764, sb:cb186, MGC174782, wu:fa20h05, wu:fa95h10, wu:fb96c06, DKFZp468F2127

Anwendungen

Applikationshinweise: WB 1ug/ml (Hu), IHC-P 2ug/ml (Hu). Antigen Retrieval by heat

Reinheit: Immunogen affinity purified.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .

Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml.

Beschränkungen: Nur für Forschungszwecke einsetzbar