Fibroblast Growth Factor Receptor 2 (FGFR2) Antikörper

Antigen: Fibroblast Growth Factor Receptor 2 (FGFR2)

Synonyme: Fgfr2, BEK, JWS, CEK3, CFD1, ECT1, KGFR, TK14, TK25, BFR-1, CD332, K-SAM, FLJ98662, Bek, svs, Fgfr7, Fgfr-2, Fgfr-7, KGFRTr, AU043015, AW556123, MGC102519, wu:fc56c05, FGFR2, cek3, FGF-R, FGFR2IIIb, fgfr72IIIb, FGFR, bek, jws, cfd1, ect1, kgfr, tk14, tk25, bfr-1, cd332, k-sam, xfgfr2, DKFZp469H1521

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Ratte (Rattus), Maus

Applikation: Western Blot (WB), Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN343359

Produktbeschreibung

Weitere Bezeichnung: Fibroblast growth factor receptor 2, FGFR2

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human FGFR2, identical to the related rat and mouse sequence.

Format: Affinity-purified

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Fibroblast growth factor receptor 2 (FGFR2) is a receptor for fibroblast growth factor encoded on a gene residing on chromosome 10. FGFR2 has also been designated as CD332. FGFR2 is a membrane-spanning tyrosine kinase that serves as a high affinity receptor for several members of the fibroblast growth factor (FGF) family. Its signals are absolutely required for vertebrate limb induction and that an FGFR2 signal is essential for the reciprocal regulation loop between FGF8 and FGF10 during limb induction. 1 FGFR2 contributes to the outgrowth, differentiation, and maintenance of the inner cell mass and raise the possibility that this activity is mediated by FGF4 signals transmitted by FGFR2. The role of early FGF signaling in pregastrulation development as a possible adaptation to mammalian (amniote) embryogenesis is discussed. 2

Spezifität: Human, rat, mouse. No cross reactivity with other proteins.

Synonyme: Fgfr2, BEK, JWS, CEK3, CFD1, ECT1, KGFR, TK14, TK25, BFR-1, CD332, K-SAM, FLJ98662, Bek, svs, Fgfr7, Fgfr-2, Fgfr-7, KGFRTr, AU043015, AW556123, MGC102519, wu:fc56c05, FGFR2, cek3, FGF-R, FGFR2IIIb, fgfr72IIIb, FGFR, bek, jws, cfd1, ect1, kgfr, tk14, tk25, bfr-1, cd332, k-sam, xfgfr2, DKFZp469H1521

Anwendungen

Applikationshinweise: WB 1ug/ml (Hu, Rat Ms), IHC-P 2ug/ml (Hu, Rat, Ms). Antigen Retrieval by heat

Reinheit: Immunogen affinity purified.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .

Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml.

Beschränkungen: Nur für Forschungszwecke einsetzbar