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CD14 Antikörper

CD14 Reaktivität: Maus ELISA Wirt: Maus Monoclonal biG53 unconjugated
Produktnummer ABIN343180
  • Target Alle CD14 Antikörper anzeigen
    CD14
    Reaktivität
    • 269
    • 55
    • 32
    • 30
    • 29
    • 28
    • 25
    • 24
    • 24
    • 18
    • 17
    • 14
    • 10
    • 9
    • 8
    • 8
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 225
    • 64
    • 25
    • 3
    • 1
    Maus
    Klonalität
    • 254
    • 64
    Monoklonal
    Konjugat
    • 129
    • 30
    • 24
    • 18
    • 15
    • 8
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD14 Antikörper ist unkonjugiert
    Applikation
    • 224
    • 104
    • 64
    • 59
    • 54
    • 50
    • 22
    • 22
    • 21
    • 14
    • 14
    • 13
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    Spezifität
    Membrane bound and soluble mouse CD14. The antibody blocks LPS binding to membrane bound CD14.
    Aufreinigung
    Protein A affinity column
    Immunogen
    Monocytes of mouse
    Klon
    BiG53
    Isotyp
    IgG1
    Top Product
    Discover our top product CD14 Primärantikörper
  • Applikationshinweise
    Suitable for immunostaining of CD14 positive cells and inhibition studies Binds at LPS activated mouse monocytes as well as mouse CD14 transfected cells or recombinant mouse CD14 ELISA. Inhibition of LPS binding to CD14 (Binding at LPS binding site). Up to 1 ug/ml biG53 inhibit binding of FITC-LPS (0.5ug/ml) to 6 x 105 CD14+CHO transfectants (FACS), Binding titre at mouse CD14 transfected CHO-cells: more than 20.000 (ELISA, Flow cytometry)
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with bidistilled water
    Konzentration
    1 mg/mL
    Buffer
    PBS, pH 7.16
    Konservierungsmittel
    Without preservative
    Lagerung
    -20 °C,-80 °C
  • Target
    CD14
    Andere Bezeichnung
    CD14 (CD14 Produkte)
    Synonyme
    CD14 molecule antikoerper, CD14 antigen antikoerper, CD14 antikoerper, Cd14 antikoerper
    Hintergrund
    Background: biG 53 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.
    Gen-ID
    12475
    NCBI Accession
    NP_033971
    UniProt
    P10810
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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