B-Cells Antikörper (FITC)

Antigen: B-Cells

Klonalität: Monoklonal

Wirt: Maus

Reaktivität: Human

Konjugat: FITC

Applikation: Durchflusszytometrie (FACS)

Produktnummer: ABIN340006

Produktbeschreibung

Weitere Bezeichnung: B cells

Immunogen: Cells, HRIK cells - Human B-Lymphoblastoid line.

Isotyp: IgM

Beschreibung: Gene: B cells

Spezifität: 3H565 recognizes a glycoprotein antigen of 105kD expressed by B lymphocytes. The 3H565 antigen is expressed by peripheral B lymphocytes and has been used widely in the study of B cell malignancy. 3H565 has been used extensively to differentiate various types of B cell malignancy. B-CLL is generally considered to be negative for 3H565 expression, but strong staining is seen in many other types of B cell lymphoma, including prolymphocytic leukaemia and hairy cell leukaemia. The nature of the 3H565 antigen has remained poorly defined following its first description in 1981. The expression pattern closely corresponds to that seen with CD22, but studies have shown that 3H565 does not recognize the CD22 molecule itself. A recent publication by Serke et al has shown that 3H565 recognizes a conformational epitope on the CD20 molecule, most likely a multimeric complex of CD20.

Anwendungen

Applikationshinweise: Flo

Reinigung: Purified

Buffer: 1 M Tris-HCL, 0.5 ml sodium chloride, 10 mM glycine, pH 8.0, 0.1% sodium azide, 1% BSA.

Beschränkungen: Nur für Forschungszwecke einsetzbar