Kallikrein Antikörper

Antigen: Kallikrein

Synonyme: klkr, kallikrein, KLK1E2, hpk

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA)

Produktnummer: ABIN336195

Produktbeschreibung

Weitere Bezeichnung: Kallikrein (Plasma)

Immunogen: Purified human Kallikrein

Kreuzreaktivität: Human

Beschreibung: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis andsome have potential as novel cancer and other disease biomarkers. Kallikrein 1 releasesthe vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. Low renalsynthesis and urinary excretion of tissue kallikrein have been linked to hypertension inanimals and humans and the kallikrein-kinin system may be involved in the developmentor progression of cardiovascular disease.

Spezifität: Minimal reactivity with other human serum proteins. Does not exhibit inhibitory effects against Human Kallikrein. Species: Human. Others not tested.

Anwendungen

Applikationshinweise: ELISA: In a simple indirect ELISA, using 400 ng of Kallikrein BP572 coated per well, the 50%binding was observed at an antibody dilution of 1/700. Under the same conditions, theend point titre was observed at an antibody dilution of 1/50K. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Konzentration: 2.2 mg/ml

Reinigung: Purified

Buffer: PBS, pH 7.2 containing 0.09% Sodium Azide as preservative.

Lagerung: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Beschränkungen: Nur für Forschungszwecke einsetzbar