Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) Antikörper

Antigen: Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)

Synonyme: LQT, RWS, WRS, LQT1, SQT2, ATFB1, ATFB3, JLNS1, KCNA8, KCNA9, Kv1.9, Kv7.1, KVLQT1, FLJ26167, CG12215, CG12915, CG33135, dKCNQ, DKCNQ, DmelCG33135, kcnq1, KCNQ1, kqt-3, kv7.1, Kvlqt1, kcnq1-A, KvLQT-1, xkvlqt1, zgc:158384

Klonalität: Polyklonal

Wirt: Ziege

Reaktivität: Human

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN335144

Produktbeschreibung

Weitere Bezeichnung: KCNQ1

Gen-ID: 3784

Immunogen: C-EQLTVPRRGPDEGS

Beschreibung: All names and symbols: KCNQ1, potassium voltage-gated channel, KQT-like subfamily, member 1, ATFB1, FLJ26167, JLNS1, KCNA8, KCNA9, KVLQT1, Kv1.9, Kv7.1, LQT, LQT1, RWS, SQT2, WRS, Jervell and Lange-Nielsen syndrome 1, kidney and cardiac voltage dependend K+ channel, long (electrocardiographic) QT syndrome, Ward-Romano syndrome 1, slow delayed rectifier channel subunit. Official Symbol: KCNQ1. RefSeq number(s): NP_000209.2, NP_861463.1

Spezifität: This antibody is expected to recognize both reported isoforms (NP_000209.2, NP_861463.1). Human, Dog

Synonyme: LQT, RWS, WRS, LQT1, SQT2, ATFB1, ATFB3, JLNS1, KCNA8, KCNA9, Kv1.9, Kv7.1, KVLQT1, FLJ26167, CG12215, CG12915, CG33135, dKCNQ, DKCNQ, DmelCG33135, kcnq1, KCNQ1, kqt-3, kv7.1, Kvlqt1, kcnq1-A, KvLQT-1, xkvlqt1, zgc:158384

Anwendungen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx. 60kDa band observed in Human Heart lysates (calculated MW of 61.5kDa according to NP_861463.1). Recommended concentration: 1-3µg/ml. An additional band of unknown identity was also consistently observed at 28kDa. This band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any such results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?

Reinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Lagerung: Aliquot and store at -20°C. Minimize freezing and thawing.

Forschungsgebiet: Kardiovaskuläres System, Metabolismus

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

EB09214 (1µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.