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Vimentin (VIM) Antikörper (Biotin)

Antigen

Vimentin (VIM)
Synonyme FLJ36605, MGC102095, cb28, MGC139781, VIM, vim, Vim, vime
Klonalität Monoklonal (HVimentin)
Wirt
Reaktivität
Alternativen

Human
Konjugat
Alternativen Biotin
Applikation
Alternativen Immunhistochemie (IHC)
Produktnummer ABIN334991
Menge 500ug  (Varianten)
Preis 484,62 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 5 Werktagen

Produktbeschreibung
Anwendungen Alternativen Varianten zurück nach oben

Weitere Bezeichnung Vimentin
Immunogen Purified Human Vimentin
Isotyp IgG1
Klon HVimentin
Beschreibung Vimentin expression in human malignant glioma cells depends on cellular density, algorithms of drug delivery and chemo/radio treatment. vimentin and detyrosinated microtubules provide structural support for the extensive microtentacles observed in detached tumor cells and a mechanism to promote successful metastatic spread. Primary colorectal carcinomas display aberrant expression of vimentin, and have activated Notch and TGFbeta signaling pathways. Vimentin is a strong arterial substrate for transglutaminases. Transglutaminase-mediated vimentin dimerization results in a novel unifying pathway by which vasodilatory and remodeling responses may be regulated. Ablation of vimentin expression inhibits migration and invasion of colon and breast cancer cell lines.

Anwendungen
Alternativen Varianten zurück nach oben

Applikationshinweise For intra-cellular staining, use 5-10ul/106 cells. Wash twice with PBS/Azide before adding the appropriate amount of secondary fluorescent reagent. Cross Reactivity: Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.
Reinigung Ion exchange column
Lagerung Shipping Condition: Antibody is shipped lyophilized at ambient temperature. Storage: In lyophilized form, for long periods, store at 4(C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20(C. Reconstitution: Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf Life: Two years lyophilized, one month in solution at 4(C.
Forschungsgebiet Abstammungsmarker, Zytoskelett, Neuronale Stammzellmarker, Zell-/Gewebemarker
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen
Anwendungen Varianten zurück nach oben

Alternativen zu Antigen "Vimentin (VIM)", Typ "Antikörper" finden
Wirte Kaninchen (116), Maus (106), Huhn (13), Ratte (6), Schaf (6), Ziege (2), Meerschweinchen (2)
Reaktivitäten Human (216), Ratte (Rattus) (95), Maus (86), Huhn (38), Rind (Kuh) (30), Schwein (28), Hund (11), Säugetiere (8), Hamster (7), Ziege (6), Affe (6), Amphibien (4), Potoroo (2), Katze (1), Fisch (1), Pferd (1), Primate (1), Kaninchen (1), Xenopus laevis (1)
Applikationen Western Blot (WB) (162), Immunfluoreszenz (IF) (97), Immunhistochemie (Paraffinschnitte) (IHC (p)) (77), Durchflusszytometrie (FACS) (59), Immunhistochemie (IHC) (57), ELISA (43), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (43), Immunzytochemie (ICC) (26), Immunpräzipitation (IP) (26), Enzyme Immunoassay (EIA) (23), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (4), To be determined by user (TBD) (3), Dot Blot (Dot) (2), ELISA (Detektionsantikörper) (2), Immunoelectron Microscopy (IEM) (2), Transfizierte Zellkultur (TCC) (2)
Konjugate FITC (10), Biotin (7), Alexa Fluor 488 (4), HRP (4), PE (4), Alexa Flour 488 (2), Alexa Fluor 350 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), Gold (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2), RBITC (2), DY547 (1), Dyomics 547 (1)
Epitope pSer82 (23), C-Term (2), Center (2), S82 (2), pSer33 (2), pSer38 (2), pSer50 (2), pSer55 (2), pSer6 (2), pSer71 (2), Ab-56 (1), Ab-83 (1), Fragment (1), pSer56 (1), pSer83 (1)