Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) Antikörper (Biotin)

Antigen: Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2)

Synonyme: C3DR, CD21, SLEB9

Klonalität: Monoklonal (HCD21)

Wirt: Maus

Reaktivität: Human

Konjugat: Biotin

Applikation: Immunhistochemie (IHC)

Produktnummer: ABIN334860

Produktbeschreibung

Weitere Bezeichnung: CD21

Immunogen: Purified human B-Cells

Isotyp: IgG2a

Klon: HCD21

Beschreibung: CD21 is expressed strongly on mature B cells, follicular dentritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation. Synonyms: Complement receptor type 2, Cr2, Complement C3d receptor, Epstein-Barr virus receptor, EBV receptor, CD21 antigen, CR2, C3DR, CD21, SLEB9.

Anwendungen

Applikationshinweise: Staining antibody. For staining, use 10ul/106 cells. Available Conjugates: This antibody is also available unconjugated and FITC. For staining with biotin or FITC-conjugated antibody use 5-10ul/106 cells.

Reinigung: Protein-A

Lagerung: Storage: Lyophilized: store at 4(C. After reconstitution, if not intended for use within a month, aliquot and store at -20(C. Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf Life: Two years lyophilized, one month in solution at 4(C.

Forschungsgebiet: CD Antigene, Oberflächenrezeptoren der Immunzellen

Beschränkungen: Nur für Forschungszwecke einsetzbar