Porteolipid Protein of Myelin Antikörper

Antigen: Porteolipid Protein of Myelin

Klonalität: Monoklonal (NYRPLP)

Wirt: Maus

Applikation: ELISA, Western Blot (WB), Immunhistochemie (IHC)

Produktnummer: ABIN334854

Produktbeschreibung

Immunogen: synthetic pPLP 139-151

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: NYRPLP

Beschreibung: Lipophilin is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. PLP functions in myelination. plays a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations associated with PLP gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Two transcript variants encoding distinct isoforms have been identified for PLP gene. PLP is the major myelin protein from the central nervous system and plays an important role in the formation or maintenance of the multilamellar structure of myelin. Synonyms: PLP, LIPOPHILIN, PMD, MMPL, SPG2, PLP/DM20.

Anwendungen

Applikationshinweise: By direct ELISA, 1:10,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories).

Konzentration: 1mg/ml in PBS (after reconstitution)

Reinigung: Ion exchange column

Lagerung: Shipping Condition: Antibody is shipped lyophilized at ambient temperature. Storage: In lyophilized form, for long periods, store at 4

Beschränkungen: Nur für Forschungszwecke einsetzbar