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CD8a Molecule (CD8A) Antikörper (FITC)
| Antigen | CD8a Molecule (CD8A) |
| Synonyme | CD8, MAL, p32, Leu2, Ly-2, Ly-B, Ly-35, Lyt-2, BB154331, MGC136643, zgc:136643, cd8, LOC100136450 |
| Klonalität | Monoklonal (HCD8) |
| Wirt |
Alternativen Maus |
| Reaktivität |
Alternativen Human |
| Konjugat |
Alternativen FITC |
| Applikation |
Alternativen Immunhistochemie (IHC)
|
| Produktnummer | ABIN334845 |
| Menge | 500ug (1mg/ml in PBS (after reconstitution...) (Varianten) |
| Preis | 376,92 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
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| Verfügbarkeit | Lieferung in 5 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | CD8 |
| Immunogen | Purified human PBL CD8+ T cells |
| Isotyp | IgG2a |
| Klon | HCD8 |
| Beschreibung | CD8 is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 acts as a co-receptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional CD8 is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 identifies cytotoxic/suppressor t-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of t-cell mediated killing. CD8 alpha chains binds to class-I MHC molecules alpha-3 domains. Synonyms: CD8, MAL, p32. |
Anwendungen
| Applikationshinweise | Staining antibody, weakly cytotoxic. For staining, use 10 ul/106 cells. Titer for cytotoxicity should be determined by the investigator. Available Conjugates: This antibody is also available conjugated to FITC. |
| Konzentration | 1mg/ml in PBS (after reconstitution) |
| Reinigung | Ion exchange column |
| Lagerung | Storage: Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf Life: Two years lyophilized, one month in solution at 4°C. |
| Forschungsgebiet | Immunologie, Adaptive Immunität, Hämopoetische Vorläufer, CD Antigene, Oberflächenrezeptoren der Immunzellen |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Alternativen
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