In den Warenkorb
Bestellen Sie auch über:
+49 (0)241 95 163 153
+49 (0)241 95 163 155

CD8a Molecule (CD8A) Antikörper (FITC)

Antigen

CD8a Molecule (CD8A)

Synonyme CD8, MAL, p32, Leu2, Ly-2, Ly-B, Ly-35, Lyt-2, BB154331, MGC136643, zgc:136643, cd8, LOC100136450
Klonalität Monoklonal (HCD8)
Wirt
Reaktivität
Alternativen

Human

Konjugat
Applikation
Alternativen Immunhistochemie (IHC)
Produktnummer ABIN334845
Menge 500ug  (1mg/ml in PBS (after reconstitution...)  (Varianten)
Preis 376,92 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 5 Werktagen

Produktbeschreibung

Weitere Bezeichnung CD8
Immunogen Purified human PBL CD8+ T cells
Isotyp IgG2a
Klon HCD8
Beschreibung CD8 is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 acts as a co-receptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional CD8 is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 identifies cytotoxic/suppressor t-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of t-cell mediated killing. CD8 alpha chains binds to class-I MHC molecules alpha-3 domains. Synonyms: CD8, MAL, p32.

Anwendungen

Applikationshinweise Staining antibody, weakly cytotoxic. For staining, use 10 ul/106 cells. Titer for cytotoxicity should be determined by the investigator. Available Conjugates: This antibody is also available conjugated to FITC.
Konzentration 1mg/ml in PBS (after reconstitution)
Reinigung Ion exchange column
Lagerung Storage: Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf Life: Two years lyophilized, one month in solution at 4°C.
Forschungsgebiet Immunologie, Adaptive Immunität, Hämopoetische Vorläufer, CD Antigene, Oberflächenrezeptoren der Immunzellen
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "CD8a Molecule (CD8A)", Typ "Antikörper" finden
Wirte Maus (430), Ratte (139), Kaninchen (92)
Reaktivitäten Human (356), Maus (143), Ratte (Rattus) (68), Huhn (33), Katze (27), Affe (23), Schwein (18), Hund (16), Rind (Kuh) (13), Schaf (13), Kaninchen (10), Pferd (8), Meerschweinchen (6), Pute (5), Ziege (4), Vogel (1), Ente (1)
Applikationen Durchflusszytometrie (FACS) (525), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (196), Immunpräzipitation (IP) (121), Immunhistochemie (Paraffinschnitte) (IHC (p)) (66), Immunfluoreszenz (IF) (62), Western Blot (WB) (54), ELISA (33), Immunhistochemie (IHC) (21), Immunzytochemie (ICC) (16), Funktionale Studien (Func) (9), Blockierende Antikörper (Inhibition) (6), Zytotoxizitätstest (CyTox) (6), Enzyme Immunoassay (EIA) (6), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (6), Immunoelectron Microscopy (IEM) (3), ELISA (Detektionsantikörper) (2), Dot Blot (Dot) (1), Radioimmunoassay (RIA) (1), To be determined by user (TBD) (1)
Konjugate FITC (107), Biotin (67), PE (61), APC (23), Cy5 (12), RPE (12), PE,Cy7 (8), PE,Cy5 (5), SPRD (5), Alexa Fluor 488 (4), HRP (4), PE,Cy5.5 (4), APC,Cy7 (3), Alexa Flour 488 (3), Alexa Fluor 647 (3), Cy3 (3), Cy5,PE (3), Cy5.5 (3), Cy7 (3), Gold (3), PE,Cy3 (3), Pacific Blue (3), RBITC (3), Alexa Fluor 350 (2), Alexa Fluor 555 (2), Alexa Fluor 700 (2), PE,Texas Red (TR) (2), PerCP (2), APC,Cy5.5 (1), Cy5.5,PE (1), Cy7,PE (1), DY647 (1), PE,DY590 (1), PE,DY647 (1), PE-Dyomics 590 (1), PE-Dyomics 647 (1), RPE,Cy5 (1), RPE,Cy5.5 (1), RPE,Cy7 (1)
Epitope C-Term (1), N-Term (1)