Interleukin 4 (IL4) Antikörper

Antigen: Interleukin 4 (IL4)

Synonyme: BSF1, IL-4, BCGF1, BCGF-1, MGC79402, Il-4, IL4, Il4e12, IL-2, BSF-1

Klonalität: Monoklonal

Wirt: Maus

Reaktivität: Human

Applikation: ELISA, Western Blot (WB), Immunhistochemie (IHC), Intrazellulärfärbung (IS), Immunhistochemie (IHC), Intrazellulärfärbung (IS)

Produktnummer: ABIN334836

Produktbeschreibung

Weitere Bezeichnung: Interleukin-4

Immunogen: r.Human IL-4

Isotyp: IgG2a  (Passende Sekundärantikörper)

Beschreibung: IL4 is a pleiotropic cytokine produced by activated T cells. IL4 is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. IL4, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. Synonyms: BCGF, BCDF, B cell stimulating factor, BSF-1, Lymphocyte stimulatory factor 1, IL-4, MGC79402, Binetrakin, Pitrakinra.

Anwendungen

Applikationshinweise: In direct ELISA, using alkaline phosphatase goat anti-mouse Ig (Jackson Laboratories) 1:10,000 dilution will give 0.3 O.D. No cross reactivity with murine IL-4 was reported.

Konzentration: 1mg/ml in PBS (after reconstitution)

Reinigung: Ion exchange

Lagerung: In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

Forschungsgebiet: Zytokine, Rezeptoren, Inflammation

Beschränkungen: Nur für Forschungszwecke einsetzbar