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Antikörper
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anti-CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) Antikörper
CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) Antikörper
| Antigen |
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| Synonyme |
p50, Bp50, CDW40, MGC9013, TNFRSF5, IGM, GP39, IMD3, TRAP, HIGM1, T-BAM, Tnfrsf5, AI326936, CD40 |
| Klonalität |
Monoklonal (HCD40) |
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Wirt
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Reaktivität
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Human (198), Maus (160), Ratte (Rattus) (11), Affe (7), Huhn (5), Hund (4), Schwein (4), Rind (Kuh) (1), Hamster (1), Nerz (1), Kaninchen (1), Schaf (1)
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Applikation
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Durchflusszytometrie (FACS) (294), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (49), Immunpräzipitation (IP) (45), Western Blot (WB) (43), Funktionale Studien (Func) (34), ELISA (28), Immunhistochemie (IHC) (27), Immunhistochemie (Paraffinschnitte) (IHC (p)) (25), Enzyme Immunoassay (EIA) (14), Immunfluoreszenz (IF) (10), Blockierende Antikörper (Inhibition) (6), Kostimulation (6), Immunzytochemie (ICC) (2), Blocking Antibody (Inhibition) (1), Dot Blot (Dot) (1), ELISA (Detektionsantikörper) (1), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (1)
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| Produktnummer |
ABIN334826 |
| Menge |
500ug (Varianten) |
| Preis |
276,92 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 5 Werktagen |
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Weitere Bezeichnung
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CD40
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Immunogen
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Activated Human B cells
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Isotyp
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IgG1 (Passende Sekundärantikörper)
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Klon
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HCD40
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Beschreibung
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CD40 is part of the TNF-receptor superfamily. CD40 is a necessary mediator for vast range of immune and inflammatory responses together with T cell-dependent immunoglobulin class switching, memory B cell growth, and germinal center formation. The transcription factor AKNA regulates the expression of CD40 and its ligand, which is vital for homotypic cell interactions. Adaptor protein TNFR2 interacts with CD40 and serves as a mediator of the signal transduction. The interaction of CD40 and its ligand is crucial for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is the receptor for TNFSF5/CD40L. Synonyms: p50, Bp50, CDW40, MGC9013, TNFRSF5, CD40.
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Applikationshinweise
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Staining antibody. For staining, use 10ul/106 cells. Available Conjugates: This antibody is also available conjugated to biotin and FITC. For staining with biotin or FITC-conjugated antibody use 5-10ul/106 cells.
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Reinigung
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Protein-A
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Lagerung
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Storage: Lyophilized: store at 4(C. After reconstitution, if not intended for use within a month, aliquot and store at -20(C. Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf Life: Two years lyophilized, one month in solution at 4(C.
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Forschungsgebiet
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Stammzellen, Hämopoetische Vorläufer, Adaptive Immunität, CD Antigene, Oberflächenrezeptoren der Immunzellen , Apoptose/Nekrose, Inflammation, Krebs
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40)", Typ "Antikörper" finden
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Wirte
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Maus (178), Ratte (110), Hamster (38), Kaninchen (28), Ziege (1)
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Reaktivitäten
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Human (198), Maus (160), Ratte (Rattus) (11), Affe (7), Huhn (5), Hund (4), Schwein (4), Rind (Kuh) (1), Hamster (1), Nerz (1), Kaninchen (1), Schaf (1)
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Applikationen
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Durchflusszytometrie (FACS) (294), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (49), Immunpräzipitation (IP) (45), Western Blot (WB) (43), Funktionale Studien (Func) (34), ELISA (28), Immunhistochemie (IHC) (27), Immunhistochemie (Paraffinschnitte) (IHC (p)) (25), Enzyme Immunoassay (EIA) (14), Immunfluoreszenz (IF) (10), Blockierende Antikörper (Inhibition) (6), Kostimulation (6), Immunzytochemie (ICC) (2), Blocking Antibody (Inhibition) (1), Dot Blot (Dot) (1), ELISA (Detektionsantikörper) (1), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (1)
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Konjugate
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FITC (53), Biotin (44), PE (42), APC (18), Alexa Fluor 647 (8), RPE (5), Alexa Fluor 488 (3), SPRD (3), Cy5,PE (2), Cy5.5,PE (2), PE,Cy5 (2), PerCP,Cy5.5 (2)
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Epitope
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pThr254 (1)
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