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CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) Antikörper

Antigen

CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40)

Synonyme p50, Bp50, CDW40, MGC9013, TNFRSF5, IGM, GP39, IMD3, TRAP, HIGM1, T-BAM, Tnfrsf5, AI326936, CD40
Klonalität Monoklonal (HCD40)
Wirt
Reaktivität
Alternativen

Human

Applikation
Alternativen Immunhistochemie (IHC)
Produktnummer ABIN334826
Menge 500ug  (Varianten)
Preis 276,92 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 5 Werktagen

Produktbeschreibung

Weitere Bezeichnung CD40
Immunogen Activated Human B cells
Isotyp IgG1  (Passende Sekundärantikörper)
Klon HCD40
Beschreibung CD40 is part of the TNF-receptor superfamily. CD40 is a necessary mediator for vast range of immune and inflammatory responses together with T cell-dependent immunoglobulin class switching, memory B cell growth, and germinal center formation. The transcription factor AKNA regulates the expression of CD40 and its ligand, which is vital for homotypic cell interactions. Adaptor protein TNFR2 interacts with CD40 and serves as a mediator of the signal transduction. The interaction of CD40 and its ligand is crucial for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is the receptor for TNFSF5/CD40L. Synonyms: p50, Bp50, CDW40, MGC9013, TNFRSF5, CD40.

Anwendungen

Applikationshinweise Staining antibody. For staining, use 10ul/106 cells. Available Conjugates: This antibody is also available conjugated to biotin and FITC. For staining with biotin or FITC-conjugated antibody use 5-10ul/106 cells.
Reinigung Protein-A
Lagerung Storage: Lyophilized: store at 4(C. After reconstitution, if not intended for use within a month, aliquot and store at -20(C. Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf Life: Two years lyophilized, one month in solution at 4(C.
Forschungsgebiet Stammzellen, Hämopoetische Vorläufer, Adaptive Immunität, CD Antigene, Oberflächenrezeptoren der Immunzellen , Apoptose/Nekrose, Inflammation, Krebs
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40)", Typ "Antikörper" finden
Wirte Maus (178), Ratte (110), Hamster (38), Kaninchen (28), Ziege (1)
Reaktivitäten Human (198), Maus (160), Ratte (Rattus) (11), Affe (7), Huhn (5), Hund (4), Schwein (4), Rind (Kuh) (1), Hamster (1), Nerz (1), Kaninchen (1), Schaf (1)
Applikationen Durchflusszytometrie (FACS) (294), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (49), Immunpräzipitation (IP) (45), Western Blot (WB) (43), Funktionale Studien (Func) (34), ELISA (28), Immunhistochemie (IHC) (27), Immunhistochemie (Paraffinschnitte) (IHC (p)) (25), Enzyme Immunoassay (EIA) (14), Immunfluoreszenz (IF) (10), Blockierende Antikörper (Inhibition) (6), Kostimulation (6), Immunzytochemie (ICC) (2), Blocking Antibody (Inhibition) (1), Dot Blot (Dot) (1), ELISA (Detektionsantikörper) (1), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (1)
Konjugate FITC (53), Biotin (44), PE (42), APC (18), Alexa Fluor 647 (8), RPE (5), Alexa Fluor 488 (3), SPRD (3), Cy5,PE (2), Cy5.5,PE (2), PE,Cy5 (2), PerCP,Cy5.5 (2)
Epitope pThr254 (1)