CD4 Molecule (CD4) Antikörper

Antigen: CD4 Molecule (CD4)

Synonyme: CD4, MGC165891, cd4, CD4mut, L3T4, Ly-4, p55, W3/25

Klonalität: Monoklonal (HCD4)

Wirt: Ratte

Reaktivität: Maus

Applikation: Blockierende Antikörper (Inhibition), Immunhistochemie (IHC), Funktionale Studien (Func)

Produktnummer: ABIN334784

Produktbeschreibung

Weitere Bezeichnung: CD4

Immunogen: Purified human PBL CD4+ T cells

Isotyp: IgG2b  (Passende Sekundärantikörper)

Klon: HCD4

Beschreibung: CD4 is a cell-surface glycoprotein found on the mature helper T cells and immature thymocytes, as well as on monocytes and macrophages. (Some cytotoxic T cells have CD4 protein as well.) Normally, about 65% of T cells in the blood are CD4+ (have CD4 protein protruding from their membrane). A mature T cell with either have CD4 or CD8, but not both. During one stage of development T cells develop CD4 and CD8 receptors, but they eventually are differentiated in the thymus and become more specialized. Synonyms: gp55, HLA-2, L3 / T4, Ly-4, T cell antigen T4/LEU3, T4, sCD4, CD4mut.

Anwendungen

Applikationshinweise: Blocking and staining antibody. Blocks blinding of HIV to CD4. For staining, use 10 ml/106 cells. Titer for blocking T cell activation should be determined by the investigator. Available Conjugates: This antibody is also available conjugated to biotin.

Konzentration: 1mg/ml in PBS (after reconstitution)

Reinigung: Ion exchange column

Lagerung: Storage: Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf Life: Two years lyophilized, one month in solution at 4°C.

Forschungsgebiet: Immunologie, Adaptive Immunität, Hämopoetische Vorläufer, CD Antigene, Oberflächenrezeptoren der Immunzellen

Beschränkungen: Nur für Forschungszwecke einsetzbar