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Antikörper
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anti-Integrin, alpha L (Antigen CD11A (p180), Lymphocyte Function-Associated Antig...
Integrin, alpha L (Antigen CD11A (p180), Lymphocyte Function-Associated Antigen 1; alpha Polypeptide) (ITGAL) Antikörper
| Antigen |
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| Synonyme |
CD11A, LFA-1, LFA1A, Cd11a, Ly-15, Ly-21, ITGAL, CD11a |
| Klonalität |
Monoklonal (MCD11a) |
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Wirt
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Reaktivität
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Maus (76), Human (61), Rind (Kuh) (16), Kaninchen (16), Hund (15), Pavian (13), Cynomolgus (13), Rhesusaffen (13), Schaf (13), Ratte (Rattus) (9), Schwein (2)
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Applikation
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 Alternativen Blockierende Antikörper (Inhibition), Immunhistochemie (IHC), Funktionale Studien (Func)
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| Produktnummer |
ABIN334766 |
| Menge |
500ug (1mg/ml in PBS (after reconstitution...) (Varianten) |
| Preis |
276,92 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 5 Werktagen |
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Weitere Bezeichnung
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CD11a
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Immunogen
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Enriched mouse peritoneal macrophages
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Isotyp
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IgG2b
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Klon
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MCD11a
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Beschreibung
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ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Synonyms: Integrin, alpha L, CD11A, p180, alpha polypeptide, ITGAL, LFA-1, LFA1A.
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Applikationshinweise
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Staining and blocking antibody. For staining, use 10 ul/106 cells. This antibody will block signaling through the CD11a molecule. Titer for blocking should be determined by the investigator.
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Konzentration
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1mg/ml in PBS (after reconstitution)
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Reinigung
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Ion exchange column
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Lagerung
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Storage: Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf Life: Two years lyophilized, one month in solution at 4°C.
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Forschungsgebiet
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Stammzellen, Hämopoetische Vorläufer, CD Antigene, Oberflächenrezeptoren der Immunzellen
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Integrin, alpha L (Antigen CD11A (p180), Lymphocyte Function-Associated Antigen 1; alpha Polypeptide) (ITGAL)", Typ "Antikörper" finden
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Wirte
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Maus (80), Ratte (73)
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Reaktivitäten
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Maus (76), Human (61), Rind (Kuh) (16), Kaninchen (16), Hund (15), Pavian (13), Cynomolgus (13), Rhesusaffen (13), Schaf (13), Ratte (Rattus) (9), Schwein (2)
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Applikationen
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Durchflusszytometrie (FACS) (137), Immunpräzipitation (IP) (31), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (18), Funktionale Studien (Func) (17), Immunhistochemie (IHC) (10), Blockierende Antikörper (Inhibition) (7), Immunfluoreszenz (IF) (5), Western Blot (WB) (4), Immunzytochemie (ICC) (2)
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Konjugate
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FITC (30), PE (22), Biotin (19), RPE (7), APC (5), Alexa Fluor 647 (4), Alexa Fluor 488 (3), PE,Cy5 (2), PE,Cy7 (2), Alexa Fluor 700 (1), Pacific Blue (1)
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