APEX1 Antikörper

Produktnummer ABIN6254847

Produktdetails anti-APEX1 Antikörper

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Reaktivität: Arabidopsis thaliana, Spinach

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APEX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Expected / apparent Molecular Weight of the Antigene: 25-38 kDa for A. thaliana
Antibody detection limit is 7 pg, 20 fmol, linear range of logit/logplot is 0.023-15pmol,midrange (B/Bo=50%) is 120 pg, 342 fmol .

Aufreinigung: serum

Immunogen: synthetic peptide derived from Arabidopsis thaliana tAPX (acession At1g77490) and sAPX (At1g08390) protein sequences, coupled to BSA. Five out of twelve amino acids are also identical with cAPX1 (At1g07890), cPX2 (At1g09640) and pAPX (At1g35000)

Anwendungsinformationen

Applikationshinweise: Recommended Dilution: 1 : 2000 with standard ECL (WB).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: For reconstitution add 200 µL of sterile water

Handhabung: Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
Once reconstituted make aliquots to avoid repreated freeze-thaw cycles.

Lagerung: -20 °C

Referenzen für anti-APEX1 Antikörper (ABIN6254847)

Sobrino-Plata, Carrasco-Gil, Abadía, Escobar, Álvarez-Fernández, Hernández: "The role of glutathione in mercury tolerance resembles its function under cadmium stress in Arabidopsis." in: Metallomics : integrated biometal science, Vol. 6, Issue 2, pp. 356-66, (2014) (PubMed).

Lehtima: "Nodularin uptake and induction of oxidative stress in spinach (Spinachia oleracea)." in: Journal of plant physiology, (2010) (PubMed).

Hideg, Kuos, Schreiber: "Imaging of NPQ and ROS formation in tobacco leaves: heat inactivation of the water-water cycle prevents down-regulation of PSII." in: Plant & cell physiology, Vol. 49, Issue 12, pp. 1879-86, (2008) (PubMed).

Kangasjaervi, Lepistoe, Haennikaeinen, Piippo, Luomala, Aro, Rintamaeki: "Diverse roles for chloroplast stromal and thylakoid-bound ascorbate peroxidases in plant stress responses." in: The Biochemical journal, Vol. 412, Issue 2, pp. 275-85, (2008) (PubMed).

Details zu APEX1

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Andere Bezeichnung: APX (APEX1 Produkte)

Synonyme: apex1 antikoerper, MGC76280 antikoerper, MGC79645 antikoerper, MGC78928 antikoerper, APE antikoerper, APE1 antikoerper, APEN antikoerper, APEX antikoerper, APX antikoerper, HAP1 antikoerper, REF1 antikoerper, Apex antikoerper, REF-1 antikoerper, BAP1 antikoerper, apex1a antikoerper, hm:zehn1532 antikoerper, wu:fc13d11 antikoerper, zgc:66204 antikoerper, Ref-1 antikoerper, apurinic/apyrimidinic endodeoxyribonuclease 1 antikoerper, APEX nuclease (multifunctional DNA repair enzyme) 1 antikoerper, APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog antikoerper, DNA-(apurinic or apyrimidinic site) lyase antikoerper, apurinic/apyrimidinic endonuclease 1 antikoerper, APEX1 antikoerper, apex1 antikoerper, apex1.L antikoerper, CNG03640 antikoerper, CNH01280 antikoerper, nth antikoerper, Spirs_4119 antikoerper, Palpr_0103 antikoerper, Apex1 antikoerper

Hintergrund: AGI Code: At1g77490
APX plays a key role in plant antioxidant system by reducing hydrogen peroxide to water. Cellular localization includes chloroplast (tAPX and sAPX), cytosol (cAPX) and peroxisome (pAPX).

Molekulargewicht: 25-38 kDa for A. thaliana

UniProt: Q42564, Q05431, Q1PER6, Q42592, Q42593

Pathways: DNA Reparatur, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus