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PINK1 Antikörper (Internal Region)

Verified PINK1 Reaktivität: Human WB, ELISA, FACS Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN334460
  • Target Alle PINK1 Antikörper anzeigen
    PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
    Bindungsspezifität
    • 21
    • 12
    • 12
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 90
    • 50
    • 24
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 72
    • 33
    Ziege
    Klonalität
    • 75
    • 32
    Polyklonal
    Konjugat
    • 49
    • 10
    • 9
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser PINK1 Antikörper ist unkonjugiert
    Applikation
    • 83
    • 52
    • 48
    • 18
    • 16
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Verwendungszweck
    PINK1
    Sequenz
    QGKAHLESRS YQEAQ
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Güteklasse
    Verified
    Immunogen
    Peptide with sequence C-QGKAHLESRSYQEAQ, from the internal region of the protein sequence according to NP_115785.1.
    Isotyp
    IgG
    Top Product
    Discover our top product PINK1 Primärantikörper
  • Applikationshinweise

    Western Blot: Approx. 60-65 kDa band observed in lysates of cell lines Jurkat and HeLa (calculated MW of 62.8 kDa according to NP_115785.1). Recommended concentration: 1-2 μg/mL. Primary incubation 1 hour at room temperature.

    Peptide ELISA: antibody detection limit dilution 1:16000.

    Kommentare

    Flow Cytometry: Flow cytometric analysis of Jurkat cells. Recommended concentration: 10ug/ml.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Minimize freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Choubey, Cagalinec, Liiv, Safiulina, Hickey, Kuum, Liiv, Anwar, Eskelinen, Kaasik: "BECN1 is involved in the initiation of mitophagy: it facilitates PARK2 translocation to mitochondria." in: Autophagy, Vol. 10, Issue 6, pp. 1105-19, (2014) (PubMed).

  • Target
    PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
    Andere Bezeichnung
    PINK1 (PINK1 Produkte)
    Synonyme
    BEST:GH23468 antikoerper, CG4523 antikoerper, Dmel\\CG4523 antikoerper, PINK antikoerper, PINK1 antikoerper, dPINK1 antikoerper, dPink1 antikoerper, pink1 antikoerper, wu:fc39e12 antikoerper, zgc:101729 antikoerper, BRPK antikoerper, PARK6 antikoerper, 1190006F07Rik antikoerper, AU042772 antikoerper, AW557854 antikoerper, mFLJ00387 antikoerper, PTEN-induced putative kinase 1 antikoerper, PTEN induced putative kinase 1 antikoerper, Pink1 antikoerper, PINK1 antikoerper, pink1 antikoerper
    Hintergrund
    PINK1, PTEN induced putative kinase 1 , BRPK, FLJ27236, PARK6 , protein kinase BRPK, serine/threonine-protein kinase PINK1
    Gen-ID
    65018, 68943, 298575
    NCBI Accession
    NP_115785
    Pathways
    Autophagie
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