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KDM5A Antikörper (AA 1416-1434)

KDM5A Reaktivität: Human WB, IF, FACS Wirt: Maus Monoclonal 18E8 unconjugated
Produktnummer ABIN3201015
  • Target Alle KDM5A Antikörper anzeigen
    KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))
    Bindungsspezifität
    • 15
    • 9
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1416-1434
    Reaktivität
    • 68
    • 15
    • 4
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 62
    • 5
    Maus
    Klonalität
    • 55
    • 13
    Monoklonal
    Konjugat
    • 26
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KDM5A Antikörper ist unkonjugiert
    Applikation
    • 47
    • 25
    • 17
    • 14
    • 13
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    Spezifität
    Specific to human and mouse RBP2. Can detect endogenous levels of RBP2.
    Aufreinigung
    Purified
    Sterilität
    Sterile filtered
    Immunogen
    A synthetic peptide corresponding to human RBP2, aa 1416-1434.
    Klon
    18E8
    Isotyp
    IgG2a kappa
  • Applikationshinweise
    1. Western blotting: ~1 g/mL
    2. Immunofluorescence staining
    3. Flow Cytometry: 1 g for 10^6 cells
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C
  • Lopez-Bigas, Kisiel, Dewaal, Holmes, Volkert, Gupta, Love, Murray, Young, Benevolenskaya: "Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation." in: Molecular cell, Vol. 31, Issue 4, pp. 520-30, (2008) (PubMed).

    Christensen, Agger, Cloos, Pasini, Rose, Sennels, Rappsilber, Hansen, Salcini, Helin: "RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3." in: Cell, Vol. 128, Issue 6, pp. 1063-76, (2007) (PubMed).

    Klose, Yan, Tothova, Yamane, Erdjument-Bromage, Tempst, Gilliland, Zhang, Kaelin: "The retinoblastoma binding protein RBP2 is an H3K4 demethylase." in: Cell, Vol. 128, Issue 5, pp. 889-900, (2007) (PubMed).

  • Target
    KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))
    Andere Bezeichnung
    KDM5A (KDM5A Produkte)
    Synonyme
    Jarid1a antikoerper, JARID1A antikoerper, RBBP-2 antikoerper, RBBP2 antikoerper, RBP2 antikoerper, AA409370 antikoerper, C76986 antikoerper, Rbbp2 antikoerper, lysine demethylase 5A antikoerper, lysine (K)-specific demethylase 5A antikoerper, Kdm5a antikoerper, KDM5A antikoerper
    Hintergrund
    RBP2 was originally identified as a retinoblastoma binding protein. It is also known as JARID1A (Jumonji, AT rich interactive domain 1A). RBP2 plays both negative and positive roles in RB- mediated transcriptional activation, depending on the kinds of genes and regulates differentiation by its function as an H3K4 histone demethylase.
    UniProt
    P29375
    Pathways
    Chromatin Binding, Warburg Effekt
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