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PPP2CA Antikörper (N-Term)

PPP2CA Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN319372
  • Target Alle PPP2CA Antikörper anzeigen
    PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))
    Bindungsspezifität
    • 16
    • 14
    • 13
    • 8
    • 7
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 68
    • 57
    • 47
    • 13
    • 10
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 76
    • 8
    • 4
    • 2
    • 1
    Kaninchen
    Klonalität
    • 76
    • 15
    Polyklonal
    Konjugat
    • 57
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PPP2CA Antikörper ist unkonjugiert
    Applikation
    • 76
    • 30
    • 19
    • 17
    • 15
    • 14
    • 13
    • 13
    • 13
    • 5
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Spezifität
    PP2A-alpha antibody detects endogenous levels of total PP2A-alpha protein.
    Aufreinigung
    Immunoaffinity Chromatography.
    Immunogen
    The antiserum was produced against a synthesized peptide Corresponding to the amino terminal sequence from human PP2A-alpha protein (''KQLSESQVKSL'').
    Top Product
    Discover our top product PPP2CA Primärantikörper
  • Applikationshinweise
    Western Blot (1/500-1/1000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at-20 °C.
  • Target
    PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))
    Andere Bezeichnung
    PPP2CA (PPP2CA Produkte)
    Synonyme
    PP2Ac antikoerper, PP2CA antikoerper, PP2Calpha antikoerper, RP-C antikoerper, PP2A antikoerper, R75353 antikoerper, Pp2a1 antikoerper, pp2ac antikoerper, zgc:110641 antikoerper, protein phosphatase 2 catalytic subunit alpha antikoerper, protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform antikoerper, protein phosphatase 2, catalytic subunit, alpha isozyme antikoerper, protein phosphatase 2 catalytic subunit alpha L homeolog antikoerper, protein phosphatase 2, catalytic subunit, beta isozyme antikoerper, serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antikoerper, PPP2CA antikoerper, Ppp2ca antikoerper, ppp2ca.L antikoerper, ppp2cb antikoerper, LOC471633 antikoerper, ppp2ca antikoerper
    Hintergrund
    Protein phosphatase 2A (PP2A) is the most abundant phosphatase specific for serine and threonine phosphorylation in mammalian cells. Dephosphorylation of substrates targeted by PP2A plays a vital role in a large variety of cellular processes including signal transduction, regulation of the cell cycle, gene expression and development. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit alpha serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory beta subunit.Synonyms: PP2A-alpha, Protein Phospatase 2A, Replication protein C, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
    Gen-ID
    5515
    NCBI Accession
    NP_002706
    UniProt
    P67775
    Pathways
    PI3K-Akt Signalweg, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades
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