EIF4G1 Antikörper (pSer1232)

Produktnummer ABIN319277

Produktdetails anti-EIF4G1 Antikörper

Target: EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))

Bindungsspezifität: pSer1232

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF4G1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: EIF4G (phospho-Ser1232) Antibody AP08034PU detects endogenous levels of eIF4G only when phosphorylated at Serine 1232.

Aufreinigung: Immunoaffinity Chromatography: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human eIF4G around the phosphorylation site of Serine 1232 (P-V-SP-P-L).

Anwendungsinformationen

Applikationshinweise: Western Blot (1/500-1/1000). Immunohistochemistry (1/50-1/100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at-20 °C.

Details zu EIF4G1

Target: EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))

Andere Bezeichnung: EIF4G1 / EIF4F (EIF4G1 Produkte)

Synonyme: EIF4GI antikoerper, CG10811 antikoerper, Dmel\\CG10811 antikoerper, EIF4G antikoerper, Eif4G antikoerper, deIF4G antikoerper, eIF-4G antikoerper, eIF4g antikoerper, p200 antikoerper, EIF4G1 antikoerper, wu:fb50a05 antikoerper, wu:fc60b06 antikoerper, eif4g antikoerper, CUCUMOVIRUS MULTIPLICATION 2 antikoerper, CUM2 antikoerper, EUKARYOTIC TRANSLATION INITIATION FACTOR 4G antikoerper, eukaryotic translation initiation factor 4G antikoerper, DDBDRAFT_0217646 antikoerper, DDBDRAFT_0217647 antikoerper, DDBDRAFT_0234257 antikoerper, DDB_0217646 antikoerper, DDB_0217647 antikoerper, DDB_0234257 antikoerper, NV18824 antikoerper, EIF-4G1 antikoerper, EIF4F antikoerper, P220 antikoerper, PARK18 antikoerper, p220 antikoerper, E030015G23Rik antikoerper, eIF4GI antikoerper, eukaryotic translation initiation factor 4 gamma 1 antikoerper, eukaryotic translation initiation factor 4G antikoerper, eukaryotic translation initiation factor 4 gamma, 1a antikoerper, eukaryotic translation initiation factor 4 gamma, 1 S homeolog antikoerper, eukaryotic initiation factor antikoerper, eukaryotic translation initiation factor 4 gamma antikoerper, eukaryotic translation initiation factor 4 gamma, 1 antikoerper, eukaryotic translation initiation factor 4, gamma 1 antikoerper, EIF4G1 antikoerper, eIF4G antikoerper, eif4g1a antikoerper, LOC704923 antikoerper, eif4g1.S antikoerper, EIF4G antikoerper, eIF4g antikoerper, Eif4g antikoerper, Eif4g1 antikoerper

Hintergrund: EIF4G1 (eukaryotic translation Initiation Factor 4 Gamma 1) is a component of the protein complex eIF-4 which is involved in the recognition of the mRNA cap ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of mRNA to the ribosome. eIF4G plays a critical role in protein expression and is at the center of a complex regulatory network. Together with the cap-binding protein eIF4E, it recruits the small ribosomal subunit to the 5'-end of mRNA and promotes the assembly of a functional translation initiation complex which scans along the mRNA to the translation start codon. Human eIF4G contains three consecutive HEAT domains, as well as long unstructured regions involved in multiple protein-protein interactions. The interactions of eIF4G1 with other factors are largely unknown.Synonyms: EIF4G, EIF4GI, Eukaryotic translation initiation factor 4 gamma 1, eIF-4-gamma 1, eIF-4G 1, eIF-4G1, p220

Gen-ID: 1981

NCBI Accession: NP_886553

UniProt: Q04637