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Antikörper
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anti-Hepatitis B Surface Antigen (HBSAg) (Subtype ad/ay) Antikörper
Hepatitis B Surface Antigen (HBSAg) (Subtype ad/ay) Antikörper
| Antigen |
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Epitope
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| Klonalität |
Polyklonal |
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Wirt
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Applikation
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Enzyme Immunoassay (EIA) (139), Immunhistochemie (Paraffinschnitte) (IHC (p)) (24), ELISA (23), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (22), Immunfluoreszenz (IF) (21), Western Blot (WB) (17), ELISA (Fangantikörper) (16), Immunpräzipitation (IP) (14), ELISA (Detektionsantikörper) (13), Lateral Flow Messung (LF) (12), Durchflusszytometrie (FACS) (5), Dot Blot (Dot) (3), Immunoelectron Microscopy (IEM) (3), Immunhistochemie (IHC) (3), Immunelektrophorese (IEP) (2), Immunelektronenmikroskopie (EM) (1), Radioimmunoassay (RIA) (1)
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| Produktnummer |
ABIN319172 |
| Menge |
1 mg (5.0 mg/ml) |
| Preis |
350,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Produktmerkmale
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Synonyms: HBV Large envelope protein, L glycoprotein, Large S protein, Large surface protein, HBVMajor surface antigen
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Weitere Bezeichnung
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Hepatitis B Surface Antigen / HBsAg
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Immunogen
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Hepatitis B Surface Antigen (HBsAg).
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Isotyp
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IgG
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Beschreibung
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Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage,inflammation and viral persistence. Infection also increases the risk of hepatocellularcarcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists ofpartially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or coreantigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivitybetween the two proteins has been observed. The HBV genome also encodes a DNApolymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but asthe disease progresses this antigen may no longer be present in the blood and tests forHBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronichepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specificcharacteristics of different serotypes and provides the basis of immunodetection. HBsAghas antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y andw/r allow the following combinations: adw, ayw, adr, ayr.
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Spezifität
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This antibody is reactive with the Ad and Ay serotypes of the Hepatitis B Virus.
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Applikationshinweise
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ELISA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Konzentration
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5.0 mg/ml
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Reinigung
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Purified
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Buffer
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PBS containing 0.09% Sodium Azide as preservative
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Lagerung
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Hepatitis B Surface Antigen (HBSAg)", Typ "Antikörper" finden
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Wirte
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Maus (158), Ziege (28), Kaninchen (18), Pferd (2)
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Reaktivitäten
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Hepatitis B (HBV) (56), Human (27)
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Applikationen
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Enzyme Immunoassay (EIA) (139), Immunhistochemie (Paraffinschnitte) (IHC (p)) (24), ELISA (23), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (22), Immunfluoreszenz (IF) (21), Western Blot (WB) (17), ELISA (Fangantikörper) (16), Immunpräzipitation (IP) (14), ELISA (Detektionsantikörper) (13), Lateral Flow Messung (LF) (12), Durchflusszytometrie (FACS) (5), Dot Blot (Dot) (3), Immunoelectron Microscopy (IEM) (3), Immunhistochemie (IHC) (3), Immunelektrophorese (IEP) (2), Immunelektronenmikroskopie (EM) (1), Radioimmunoassay (RIA) (1)
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Konjugate
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HRP (12), Biotin (7), FITC (5)
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Epitope
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ad/ay (47), AA 132-137 (31), Subtype ad/ay (4), ayw (4), adw/ayw (2), ay (2), Subtype ay (1), Subtype ayw (1), ad (1)
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Alternativen 
