GRIA2 Antikörper

Produktnummer ABIN319147

Produktdetails anti-GRIA2 Antikörper

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Reaktivität: Human, Ratte, Maus, Zebrafisch (Danio rerio), Huhn, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody is specific for glutamate receptor subunit 2 (GluR2), a component of the AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid) group of ionotropic glutamate receptors, which play a key role at excitatory synapses, including synaptic transmission, stabilisation and plasticity.

Aufreinigung: Affinity chromatography

Immunogen: Keyhole limpet haemocyanin conjugated synthetic peptide corresponding to an amino acid sequence within rat GluR2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1: 1000, detects a band of approximately 100 kDa in rat brain hippocampuscell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM Hepes, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin, 50 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GRIA2

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Andere Bezeichnung: Glutamate Receptor 2 / GLUR2 (GRIA2 Produkte)

Synonyme: GLUR2 antikoerper, GLURB antikoerper, GluA2 antikoerper, GluR-K2 antikoerper, HBGR2 antikoerper, GluR-2 antikoerper, GluR-B antikoerper, Glur-2 antikoerper, Glur2 antikoerper, GluR2 antikoerper, gluR-B antikoerper, glur2a antikoerper, gria2.1 antikoerper, zfGRIA2[a] antikoerper, glur2 antikoerper, glutamate ionotropic receptor AMPA type subunit 2 antikoerper, glutamate receptor, ionotropic, AMPA 2 antikoerper, glutamate receptor, ionotropic, AMPA2 (alpha 2) antikoerper, glutamate receptor, ionotropic, AMPA 2a antikoerper, glutamate receptor, ionotropic, AMPA 2 S homeolog antikoerper, GRIA2 antikoerper, Gria2 antikoerper, gria2a antikoerper, gria2.S antikoerper

Hintergrund: GluR2 is possibly the most important of the AMPA receptor subunits, responsible for AMPA receptor rectifying properties, control of ion flow and in particular the influx of calcium. The majority of GluR2 in the CNS is expressed in the GluR2(R) form, containing a critical arginine residue (as opposed to a glutamine residue) in the Transmembrane region 2 (TM2) domain, thereby rendering native AMPA receptors impermeable to calcium.Synonyms: AMPA-selective glutamate receptor 2, AMPA2, GRIA2, GluR-B, GluR-K2, Glutamate receptor ionotropic

Gen-ID: 2891

NCBI Accession: NP_000817

UniProt: P42262

Pathways: PI3K-Akt Signalweg