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Antikörper
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anti-Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) Antikörper
Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) Antikörper
| Antigen |
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| Synonyme |
KIP1, MEN4, CDKN4, MEN1B, P27KIP1, p27, Rpn4, MGC8644, Kip1, Cdki1b, sb:cb611, wu:fb63g10, wu:fb64g10, wu:fe18e03, CDKN1B |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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 Alternativen Enzyme Immunoassay (EIA), Immunpräzipitation (IP), Western Blot (WB)
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| Produktnummer |
ABIN318813 |
| Menge |
50 µl |
| Preis |
260,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Produktmerkmale
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Synonyms: p27Kip1, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27
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Weitere Bezeichnung
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CDKN1B / KIP1
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Swiss-Prot
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P46527
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Immunogen
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Full length human p27 protein
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Kreuzreaktivität
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Human
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Isotyp
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IgG (Passende Sekundärantikörper)
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Beschreibung
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P27 is a cyclin dependent kinase inhibitor (CKI) which controls G1/S phase transition in thecell cycle. p27 prevents cell cycle progression by inhibiting the activity of cyclin E-Cdk2 andcyclin D-Cdk4/6, thus preventing E2F activation and S phase progression. Low p27 levels and/or cytosolic mis-localisation have been associated with thedevelopment of lung, breast, colon, oesophagus, and prostate tumours.
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Spezifität
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This antibody detects p27, a member of the Kip/Cip family of proteins which is also knownas p27 kip1. Species: Human. Others not tested.
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Applikationshinweise
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ELISA. Immunoprecipitation. Western Blot: 1: 2000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Reinigung
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Serum
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Lagerung
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.
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Forschungsgebiet
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Krebs, Zellzyklus
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B)", Typ "Antikörper" finden
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Wirte
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Kaninchen (60), Maus (20), Ziege (8), Huhn (2)
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Reaktivitäten
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Human (81), Maus (36), Ratte (Rattus) (32), Hund (5), Affe (2), Katze (1), Huhn (1), Rind (Kuh) (1)
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Applikationen
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Western Blot (WB) (75), Immunhistochemie (Paraffinschnitte) (IHC (p)) (38), Immunpräzipitation (IP) (18), Enzyme Immunoassay (EIA) (17), ELISA (10), Immunfluoreszenz (IF) (10), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (9), Immunhistochemie (IHC) (9), ELISA (Detektionsantikörper) (5), Dot Blot (Dot) (3)
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Epitope
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pThr187 (5), internal (2), pSer178 (2), pThr157 (2), pThr198 (2), C-Term (1), T198 (1), pS10 (1), pS178 (1), pSer10 (1), pT157 (1), pT187 (1)
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