HAVCR1 Antikörper (Hepatitis A Virus Cellular Receptor 1) (Middle Region)

Details for Product anti-HAVCR1 Antibody No. ABIN318766, Anbieter: Anmelden zum Anzeigen
Antigen
  • HAVCR1
  • LOC100226241
  • AI503787
  • KIM-1
  • TIM-1
  • Tim1
  • Timd1
  • HAVCR
  • HAVCR-1
  • KIM1
  • TIM
  • TIM1
  • TIMD-1
  • TIMD1
  • Kim1
  • hepatitis A virus cellular receptor 1
  • Rho guanine nucleotide exchange factor (GEF) 5
  • RCJMB04_10h2
  • HAVCR1
  • LOC100226241
  • Havcr1
  • Arhgef5
Epitop
Middle Region
18
9
8
8
7
7
6
6
6
5
5
5
5
5
5
5
4
4
3
3
3
3
2
2
2
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
91
41
25
11
6
1
1
1
Wirt
Kaninchen
108
34
8
5
Klonalität
Polyklonal
Konjugat
Dieser HAVCR1 Antikörper ist unkonjugiert
13
11
5
5
3
3
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
109
88
20
19
18
11
7
4
4
4
2
2
1
1
Optionen
Hersteller
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Immunogen 16 amino acid peptide sequence near the centre of human TIM-1.
Isotyp IgG
Spezifität This antibody detects T cell immunoglobulin mucin-1 (TIM-1), which was first identified as the receptor used by hepatitis A for viral entry (it is also known as the hepatitis A virus cellular receptor- HAVCR).
Reinigung Purified
Andere Bezeichnung TIMD1 / HAVCR1 (HAVCR1 Antibody Abstract)
Hintergrund TIM-1 is a key cell surface protein that binds TIM-4, leading to T cell proliferation and T helper type 2 (Th2) cytokine production. TIM-1 has also been shown to bind and activate macrophages. Two splice variants for human TIM-1 exist, TIM-1a is predominantly expressed in the liver, whilst TIM-1b is expressed in the kidney. Expression of TIM-1 in the kidney is thought to be upregulated in damaged tissue, and is thought to assist healing. TIM-1 polymorphisms are associated with asthma.Synonyms: HAVCR-1, Hepatitis A virus cellular receptor 1, T cell immunoglobulin and mucin domain-containing protein 1, T cell membrane protein 1, TIM-1, TIM1, TIMD-1
Gen-ID 26762
NCBI Accession NP_001092884
UniProt Q96D42
Applikationshinweise Western Blot: 1.0 - 2.0g/mL, detects a band of approximately 49 kDa in human uterustissue lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1.0 mg/mL
Buffer Phosphate buffered saline containing 0.02 % Sodium Azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.
Bilder des Herstellers
 image for anti-HAVCR1 Antikörper (Hepatitis A Virus Cellular Receptor 1) (Middle Region) (ABIN318766) anti-Hepatitis A Virus Cellular Receptor 1 (HAVCR1) (Middle Region) antibody
Allgemeine Veröffentlichungen Hein, Woods: "TIM-1 regulates macrophage cytokine production and B7 family member expression." in: Immunology letters, Vol. 108, Issue 1, pp. 103-8, 2006 (PubMed).

Meyers, Sabatos, Chakravarti, Kuchroo: "The TIM gene family regulates autoimmune and allergic diseases." in: Trends in molecular medicine, Vol. 11, Issue 8, pp. 362-9, 2005 (PubMed).