14-3-3 Pan Antikörper
| Antigen |
|
| Klonalität |
Polyklonal |
|
Wirt
|
|
|
Reaktivität
|
|
|
Applikation
|
Alternativen Immunpräzipitation (IP), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)
|
| Produktnummer |
ABIN318725 |
| Menge |
0.1 ml (Varianten) |
| Preis |
400,00 € Zzgl. Versandkosten €20,00 und MWSt
|
| Lieferung nach |
|
| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
|
Produktmerkmale
|
Synonyms: YWHA, Protein kinase C inhibitor protein 1
|
|
Weitere Bezeichnung
|
14-3-3 protein pan
|
|
Immunogen
|
Synthetic correspsonding to all isoforms of sheep 14-3-3.
|
|
Kreuzreaktivität
|
Rind (Kuh), Human, Maus, Ratte (Rattus), Schaf
|
|
Isotyp
|
IgG (Passende Sekundärantikörper)
|
|
Beschreibung
|
The 14-3-3 family consists of 30kD proteins that are involved in multiple cellular processesincluding protein kinase signalling pathways, regulation of cell cycle progression,transcription and intracellular trafficking. Protein interactions with 14-3-3 show distinctpreferences for its different isoforms and are regulated by phosphorylation of both 14-3-3and the bound protein.
|
|
Spezifität
|
This antibody recognises all isoforms of the 14-3-3 protein family. Species: Sheep, Human, Bovine, Rat, Mouse. Others not tested.
|
|
Applikationshinweise
|
Immunohistochemistry on paraffin sections: does not require antigen retrieval using heattreatment prior to staining of paraffin sections. Immunoprecipitation. Western Blot: detects a band of approximately 30kDa in HEK293 cell lysates. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
|
|
Reinigung
|
Serum
|
|
Lagerung
|
Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.
|
|
Forschungsgebiet
|
Transkriptionsfaktoren
|
|
Beschränkungen
|
Nur für Forschungszwecke einsetzbar
|
Alternativen zu Antigen "14-3-3 Pan", Typ "Antikörper" finden
|
Wirte
|
Kaninchen (8), Maus (2), Schaf (2)
|
|
Reaktivitäten
|
Human (8), Ratte (Rattus) (7), Maus (6), Rind (Kuh) (5), Xenopus laevis (5), Huhn (3), Hund (3), Schaf (3), Affe (2), Primate (1)
|
|
Applikationen
|
Western Blot (WB) (10), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (2), Immunpräzipitation (IP) (2), Immunfluoreszenz (IF) (1), Immunhistochemie (Paraffinschnitte) (IHC (p)) (1)
|
|
Epitope
|
pSer58 (4), C-Term (1), pSer185 (1)
|