RNF144A
Reaktivität: Human
WB, ELISA, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
RNF144 antikoerper, UBCE7IP4 antikoerper, AI316797 antikoerper, Rnf144 antikoerper, UIP4 antikoerper, Ubce7ip4 antikoerper, RGD1561737 antikoerper, rnf144 antikoerper, rnf144a antikoerper, si:dkeyp-7f8.1-001 antikoerper, wu:fj49a04 antikoerper, zgc:92582 antikoerper, ring finger protein 144A antikoerper, ring finger protein 144ab antikoerper, RNF144A antikoerper, Rnf144a antikoerper, rnf144ab antikoerper
Hintergrund
Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction.The three classes of enzymes involved in ubiquitination are the ubiquitinactivating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). UBCE7IP4 (Ubiquitin-conjugating enzyme 7- interacting protein 4), also known as RNF144A (RING finger protein 144A), KIAA0161 or RNF144, is a 292 amino acid single-pass membrane protein that contains one RING-type zinc finger and two IBR-type zinc fingers. Functioning as an E3 ubiquitin-protein ligase, UBCE7IP4 accepts ubiquitin (in the form of a thioester) from E2 ubiquitin-conjugating enzymes, such as UBC8 and UBCH7, and transfers that ubiquitin residue to target substrates. Via its RING finger, UBCE7IP4 may play a role in protein-DNA and protein-protein interactions throughout the cell.Synonyms: KIAA0161, Probable E3 ubiquitin-protein ligase RNF144A, RING finger protein 144A, RNF144, UbcM4-interacting protein 4, Ubiquitin-conjugating enzyme 7-interacting protein 4, Uip4