HNF4A Antikörper

Produktnummer ABIN317780

Produktdetails anti-HNF4A Antikörper

Target: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNF4A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of HNF4α protein.(region surrounding Lys298)

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-HNF4A Antikörper (ABIN317780)

Hu, Ma, Huang, Mao, Yang, Zhao, Li, Qiu, Yang, Zheng, Wang: "Dihydrocapsaicin Attenuates Plaque Formation through a PPAR?/LXR? Pathway in apoE(-/-) Mice Fed a High-Fat/High-Cholesterol Diet." in: PLoS ONE, Vol. 8, Issue 6, pp. e66876, (2013) (PubMed).

He, Xiao, Zhang, Ma, Li, Yang: "Detection and functional annotation of misregulated microRNAs in the brain of the Ts65Dn mouse model of Down syndrome." in: Chinese medical journal, Vol. 126, Issue 1, pp. 108-13, (2013) (PubMed).

Details zu HNF4A

Target: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Andere Bezeichnung: HNF4 alpha / TCF14 (HNF4A Produkte)

Synonyme: HNF4A antikoerper, HNF4alpha antikoerper, CG9310 antikoerper, DmHNF4 antikoerper, Dmel\\CG9310 antikoerper, HNF-4 antikoerper, HNF-4(D) antikoerper, HNF4 antikoerper, Hnf-4 antikoerper, Hnf-4h antikoerper, NR2A4 antikoerper, dHNF-4 antikoerper, dHNF4 antikoerper, Hnf4 antikoerper, Hnf4alpha antikoerper, MODY1 antikoerper, Nr2a1 antikoerper, Tcf14 antikoerper, HNF4a7 antikoerper, HNF4a8 antikoerper, HNF4a9 antikoerper, MODY antikoerper, NR2A1 antikoerper, NR2A21 antikoerper, TCF antikoerper, TCF14 antikoerper, HNF-4alpha antikoerper, fb58h09 antikoerper, id:ibd1279 antikoerper, wu:fb58h09 antikoerper, hnf4 antikoerper, nr2a1 antikoerper, hepatocyte nuclear factor 4 alpha antikoerper, Hepatocyte nuclear factor 4 antikoerper, hepatic nuclear factor 4, alpha antikoerper, hepatocyte nuclear factor 4, alpha antikoerper, hepatocyte nuclear factor 4 alpha S homeolog antikoerper, HNF4A antikoerper, hnf4a antikoerper, Hnf4 antikoerper, Hnf4a antikoerper, hnf4a.S antikoerper

Hintergrund: HNF-1 (α and β), HNF-3 (α, β and γ), HNF-4 (α and γ), and HNF-6 compose, in part, a homoeprotein family designated the Hepatocyte Nuclear Factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. HNF-3α, HNF-3β and HNF-3γ regulate the transcription of numerous hepatocyte genes in adult liver. HNF-3α and HNF-3β have also been shown to be involved in gastrulation events such as body axis formation. HNF-4α and HNF-4γ have been shown to be important for early embryo development. HNF-4α is expressed in liver, kidney, pancreas, small intestine, testis and colon, and HNF-4γ is expressed in each of these tissues except liver. HNF-6 has been shown to bind to the promoter of HNF-3β, which indicates a potential role of HNF-6 in gut endoderm epithelial cell differentiation. Evidence suggests that HNF-6 may also be a transriptional activator for at least 22 other hepatocyte-enriched genes, including cytochrome P450 2C13 and α-1 antitrypsin.Synonyms: HNF4, HNF4A, Hepatocyte nuclear factor 4-alpha, NR2A1, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14, Transcription factor HNF-4

Molekulargewicht: 52 kDa

Gen-ID: 3172

NCBI Accession: NP_000448

UniProt: P41235

Pathways: AMPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process