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A Kinase (PRKA) Anchor Protein 13 (AKAP13) Antikörper

Antigen

A Kinase (PRKA) Anchor Protein 13 (AKAP13)

Synonyme
BRX, LBC, HA-3, Ht31, c-lbc, AKAP-Lbc, ARHGEF13, FLJ11952, FLJ43341, PROTO-LB, PROTO-LBC, 1700026G02Rik, 5730522G15Rik, 5830460E08Rik, AKAP13, brx, lbc, ha-3, ht31, MGC81410, akap-lbc, arhgef13, proto ... mehr anzeigen
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Human

Applikation
Alternativen Immunhistochemie (Gefrierschnitte) (IHC (fro)), Enzyme Immunoassay (EIA), Western Blot (WB)
Produktnummer ABIN314475
Menge 0.1 mg  (1 mg/ml)  (Varianten)
Preis 400,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Weitere Bezeichnung AKAP13
Gen-ID 11214
Beschreibung The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range ofsubstrates. Specificity of PKA signaling is thought to be mediated by thecompartmentalization of the kinase to specific sites within the cell. To maintain thisspecific localization, the R subunit (RII) of PKA interacts with specific RII-anchoringproteins. The family of RII-anchoring proteins has been designated A-kinase anchoringproteins (AKAP). AKAP 13, also known as Brx (breast cancer nuclear receptor-bindingau xiliary protein), Lbc (lymphoid blast crisis oncogene), HA-3 or Ht31 (humanthyroid-anchoring protein 31), functions as a cAMP-dependent scaffold anchor for PKAand also has Rho-GEF activity. It is known to regulate TLR2 signaling, NFkappaBactivation, protein kinase D activation and participate in Actin stress fiber formation.Seven isoforms exist for AKAP 13 and, depending on the isoform, it localizes to thecytoplasm, nucleus or cell membrane.
Spezifität AKAP 13 (D738) detects endogenous levels of AKAP 13 protein. Species Reactivity: This antibody is reactive against Human.
Synonyme BRX, LBC, HA-3, Ht31, c-lbc, AKAP-Lbc, ARHGEF13, FLJ11952, FLJ43341, PROTO-LB, PROTO-LBC, 1700026G02Rik, 5730522G15Rik, 5830460E08Rik, AKAP13, brx, lbc, ha-3, ht31, MGC81410, akap-lbc, arhgef13, proto-lb, proto-lbc

Anwendungen

Applikationshinweise Suggested working dilutions: ELISA 1:20000-1:40000,Western Blot 1:500-1:1000,immunohistochemistry 1:50-1:200
Konzentration 1 mg/ml
Buffer Phosphate buffered saline, pH 7.2. Preservative: 15 mM sodium azide.
Lagerung Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Forschungsgebiet Kardiovaskuläres System, Hypertrophie
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "A Kinase (PRKA) Anchor Protein 13 (AKAP13)", Typ "Antikörper" finden
Wirte Maus (7), Kaninchen (7)
Reaktivitäten Human (14), Ratte (Rattus) (1)
Applikationen Western Blot (WB) (11), Enzyme Immunoassay (EIA) (4), Immunhistochemie (Paraffinschnitte) (IHC (p)) (4), ELISA (3), ELISA (Detektionsantikörper) (2), Immunfluoreszenz (IF) (2), Immunhistochemie (IHC) (2), Immunpräzipitation (IP) (2)