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A Kinase (PRKA) Anchor Protein 13 (AKAP13) Antikörper
| Antigen | A Kinase (PRKA) Anchor Protein 13 (AKAP13) |
| Synonyme |
BRX, LBC, HA-3, Ht31, c-lbc, AKAP-Lbc, ARHGEF13, FLJ11952, FLJ43341, PROTO-LB, PROTO-LBC, 1700026G02Rik, 5730522G15Rik, 5830460E08Rik, AKAP13, brx, lbc, ha-3, ht31, MGC81410, akap-lbc, arhgef13, proto ...
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| Klonalität | Polyklonal |
| Wirt |
Alternativen Kaninchen |
| Reaktivität |
Alternativen Human |
| Applikation |
Alternativen Immunhistochemie (Gefrierschnitte) (IHC (fro)), Enzyme Immunoassay (EIA), Western Blot (WB)
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| Produktnummer | ABIN314475 |
| Menge | 0.1 mg (1 mg/ml) (Varianten) |
| Preis | 400,00 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
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| Verfügbarkeit | Lieferung in 7 bis 10 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | AKAP13 |
| Gen-ID | 11214 |
| Beschreibung | The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range ofsubstrates. Specificity of PKA signaling is thought to be mediated by thecompartmentalization of the kinase to specific sites within the cell. To maintain thisspecific localization, the R subunit (RII) of PKA interacts with specific RII-anchoringproteins. The family of RII-anchoring proteins has been designated A-kinase anchoringproteins (AKAP). AKAP 13, also known as Brx (breast cancer nuclear receptor-bindingau xiliary protein), Lbc (lymphoid blast crisis oncogene), HA-3 or Ht31 (humanthyroid-anchoring protein 31), functions as a cAMP-dependent scaffold anchor for PKAand also has Rho-GEF activity. It is known to regulate TLR2 signaling, NFkappaBactivation, protein kinase D activation and participate in Actin stress fiber formation.Seven isoforms exist for AKAP 13 and, depending on the isoform, it localizes to thecytoplasm, nucleus or cell membrane. |
| Spezifität | AKAP 13 (D738) detects endogenous levels of AKAP 13 protein. Species Reactivity: This antibody is reactive against Human. |
| Synonyme | BRX, LBC, HA-3, Ht31, c-lbc, AKAP-Lbc, ARHGEF13, FLJ11952, FLJ43341, PROTO-LB, PROTO-LBC, 1700026G02Rik, 5730522G15Rik, 5830460E08Rik, AKAP13, brx, lbc, ha-3, ht31, MGC81410, akap-lbc, arhgef13, proto-lb, proto-lbc |
Anwendungen
| Applikationshinweise | Suggested working dilutions: ELISA 1:20000-1:40000,Western Blot 1:500-1:1000,immunohistochemistry 1:50-1:200 |
| Konzentration | 1 mg/ml |
| Buffer | Phosphate buffered saline, pH 7.2. Preservative: 15 mM sodium azide. |
| Lagerung | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Forschungsgebiet | Kardiovaskuläres System, Hypertrophie |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Alternativen
Alternativen zu Antigen "A Kinase (PRKA) Anchor Protein 13 (AKAP13)", Typ "Antikörper" finden
| Wirte | Maus (7), Kaninchen (7) |
| Reaktivitäten | Human (14), Ratte (Rattus) (1) |
| Applikationen | Western Blot (WB) (11), Enzyme Immunoassay (EIA) (4), Immunhistochemie (Paraffinschnitte) (IHC (p)) (4), ELISA (3), ELISA (Detektionsantikörper) (2), Immunfluoreszenz (IF) (2), Immunhistochemie (IHC) (2), Immunpräzipitation (IP) (2) |




Alternativen