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Beschreibung
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The protein encoded by this gene is a member of the beta chemokine receptor family. Itis predicted to be a seven transmembrane protein similar to G protein coupledreceptors. Chemokines and their receptors are key regulators of the thymocytesmigration and maturation in normal and inflammation conditions. This gene is expressedin a range of tissues and hemopoietic cells. The expression of this receptor in lymphaticendothelial cells and over expression in vascular tumors suggested its function inchemokine-driven recirculation of leukocytes and possible chemokine effects on thedevelopment and growth of vascular tumors. This receptor appears to bind the majorityof beta-chemokine family members, however, its specific function remains unknown.The specific ligand of this receptor is CCL25. It has been found that this gene isdifferentially expressed by T lymphocytes of small intestine and colon, suggested a rolein the thymocytes recruitment and development that may permit functional specializationof immune responses in different segment of the gastrointestinal tract. This gene ismapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptorgenes. Two alternatively spliced transcript variants have been described. Alternate Names: anti-C C chemokine receptor D6 antibody, anti-C C chemokine receptor type 9 antibody,anti-C C CKR 9 antibody, anti-CC Chemokine receptor CCR10 antibody, anti-CC CKR 9antibody, anti-CCBP2 antibody, anti-CCCKR9 antibody, anti-CCR 9 antibody,anti-CCR9 antibody, anti-CDw199 antibody, anti-CDw199 antigen antibody,anti-Chemokine C C motif receptor 9 antibody, anti-Chemokine CC Motif Receptor 9antibody, anti-Chemokine receptor CCR 9 antibody, anti-Chemokine-binding protein D6antibody, anti-CMKBR9 antibody, anti-G protein coupled receptor 28 antibody, anti-GPR28 antibody, anti-GPR 9 6 antibody, anti-GPR28 antibody, anti-GPR96 antibody.
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Alternativen 
