RIG-1 Antikörper

Antigen: RIG-1

Klonalität: Monoklonal (SS1A)

Wirt: Ratte

Reaktivität: Maus

Applikation: Western Blot (WB)

Produktnummer: ABIN314101

Produktbeschreibung

Immunogen: Peptide-KLH, C-terminal end of murine RIG-1

Format: Purified

Isotyp: IgG2a, kappa chain  (Passende Sekundärantikörper)

Klon: SS1A

Beschreibung: RIG-1/DDX58(Retinoic acid-inducible gene 1 protein/ DEAD-box protein 58)is an RNA helicase that belongs to the DEAD/H box. Contains 2 CARDdomains, a helicase ATP-binding domain and a helicase C-terminal domain.Predicted molecular weight approximately 107 kD. RIG-1 has an essentialfunction in double-stranded RNA-induced innate antiviral responses. RIG-1and MDA5 (melanoma differentiation-associated gene 5) are key intracellularreceptors that sense intracellular viral infection and trigger a signal for innateantiviral responses including the production of type I IFN. Clone SS1A hasbeen shown to be useful for western blotting of the mouse RIG-1 protein.

Anwendungen

Reinigung: This antibody was purified by affinity chromatography.

Buffer: This antibody is provided in phosphate-buffered solution, pH 7.2, containing0.09% sodium azide at 0.5 mg/ml.

Lagerung: Upon receipt, store undiluted at 4 degrees C.

Beschränkungen: Nur für Forschungszwecke einsetzbar