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Jun Proto-Oncogene (JUN) (pTyr91/Tyr93) Antikörper

Antigen

Jun Proto-Oncogene (JUN)
Synonyme AP1, AP-1, c-Jun, fj36h07, zgc:65863, wu:fj36h07, jun
Epitope
Alternativen

pTyr91/Tyr93
Klonalität Monoklonal (C-J4C4-1)
Wirt
Reaktivität
Alternativen

Maus, Ratte (Rattus)
Applikation
Alternativen Western Blot (WB)
Produktnummer ABIN314077
Menge 25 ug  (Varianten)
Preis 122,86 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 5 bis 7 Werktagen

Produktbeschreibung
Anwendungen Alternativen Sekundärantikörper Varianten zurück nach oben

Weitere Bezeichnung Phospho-C-Jun (Tyr91/Tyr93)
Immunogen Modified peptide conjugated to KLHReactivity: HumanCross-
Format Purified
Isotyp IgG1, kappa chain  (Passende Sekundärantikörper)
Klon C-J4C4-1
Beschreibung C-Jun (also known as protooncogene c-jun) is a member of the b-ZIP transcription factor, jun subfamily, containing aleucine zipper domain. This nuclear protein is ubiquitously expressed and binds the enhancer heptamer motif5',-TGA(C/G)TCA-3', to activate gene expression. c-jun interacts with c-Fos to form a functionaltranscriptional dimer, Jun deletions and translocations have been observed in human malignancies. c-jun isphosphorylated by JNK1, casein kinase II, and DNA-dependent protein kinase, phosphorylation enhancestranscriptional activity. E1A binding protein p300 acetylates and decreases the transcriptional activity of c-jun. Thereare multiple phosphorylation sites (63, 73, 231, 249) on c-jun and one reported acetylation site (271). C-jun has beenreported to interact with CREB binding protein (CBP), CREB, ATF4, c-Fos, STAT1, STAT3 and STAT4, Bcl-3,SMAD3/4 heterodimers, and TCF20. The Poly6065 antibody recognizes mouse and human c-jun and has beenshown to be useful for Western blotting

Anwendungen
Alternativen Sekundärantikörper Varianten zurück nach oben

Applikationshinweise Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s):Use 5 ug antibody per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titratedfor optimal performance for each application.
Reinigung The antibody was purified by protein G affinity chromatography
Buffer This antibody is provided in phosphate-buffered solution, pH 7.2, containing0.09% sodium azide. Final antibody concentration is 0.5 mg/ml.
Lagerung Upon receipt, store at 4 degrees C
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen
Anwendungen Sekundärantikörper Varianten zurück nach oben

Alternativen zu Antigen "Jun Proto-Oncogene (JUN)", Typ "Antikörper" finden
Wirte Kaninchen (252), Maus (9), Huhn (2)
Reaktivitäten Human (254), Maus (180), Ratte (Rattus) (158), Rind (Kuh) (8), Hund (7), Schwein (7), Huhn (5), Affe (3), Schaf (3), Fruchtfliege (Drosophila melanogaster) (2), Meerschweinchen (2), Hamster (2), Kaninchen (2), Xenopus laevis (2)
Applikationen Western Blot (WB) (243), Immunhistochemie (IHC) (97), Immunhistochemie (Paraffinschnitte) (IHC (p)) (61), Enzyme Immunoassay (EIA) (50), ELISA (30), Immunpräzipitation (IP) (27), Immunfluoreszenz (IF) (23), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (22), Dot Blot (Dot) (15), ELISA (Detektionsantikörper) (3), Durchflusszytometrie (FACS) (1)
Epitope pSer73 (16), pSer63 (12), pThr239 (10), pTyr170 (10), pThr91 (9), pThr93 (9), pSer243 (8), Ab-239 (5), Ab-243 (5), Ab-91 (5), Ab-93 (5), C-Term (3), pS63 (3), Ab 63 (2), pS73 (2), N-Term (1), S63 (1), S73 (1), Sumoylation Site (1), T239 (1), T243 (1), T249 (1), pT239 (1), pT243 (1), pT249 (1), pThr243 (1), pThr249 (1), pTyr91/Tyr93 (1), pY170 (1)