MMP-9 Antikörper

Antigen: MMP-9

Klonalität: Monoklonal (2C3)

Wirt: Maus

Reaktivität: Human

Applikation: Western Blot (WB), Immunhistochemie (IHC)

Produktnummer: ABIN314046

Produktbeschreibung

Weitere Bezeichnung: MMP9

Immunogen: Ovalbumin-conjugated synthetic Peptide KLGLGADVAQVT

Format: Purified

Isotyp: IgG1, kappa chain  (Passende Sekundärantikörper)

Klon: 2C3

Beschreibung: Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances within theextracellular matrix. The MMP family includes six different groups of enzymes: collagenases, gelatinases,stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to becleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are thought toplay an important role in tissue remodeling associated with various physiological and pathological processes. MMP9degrades of proteins in the extracellular matrix and activates growth factors like proTGFb and proTNFa. MMP-9contributes to the invasion and metastasis of various human malignancies. Clone F11P2C3 has been shown to beuseful for western blotting and immunohistochemistry of human MMP9.

Anwendungen

Applikationshinweise: Each lot of this antibody is quality control tested by Western blotting. ForWestern blotting, suggested working dilution(s): Use 5-10 ug per 5 mlantibody dilution buffer for each mini-gel. It is recommended that the reagentbe titrated for optimal performance for each application.

Reinigung: This antibody was purified by affinity chromatography.

Buffer: This antibody is provided in phosphate-buffered solution, pH 7.2, containing0.09% sodium azide at 0.5 mg/ml.

Lagerung: Upon receipt, store undiluted at 4 degrees C.

Beschränkungen: Nur für Forschungszwecke einsetzbar