Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) Antikörper

Antigen: Lectin, Galactoside-Binding, Soluble, 3 (LGALS3)

Synonyme: GAL3, MAC2, CBP35, GALBP, GALIG, LGALS2, MGC52947, MGC75803, LGALS3, MGC151898, galectin-3, Galectin-3, MGC148757, leg3

Klonalität: Monoklonal (Gal397)

Wirt: Maus

Reaktivität: Maus, Human

Applikation: Durchflusszytometrie (FACS), Western Blot (WB), Immunfluoreszenz (IF), Immunhistochemie (IHC)

Produktnummer: ABIN314033

Produktbeschreibung

Weitere Bezeichnung: Mac-2 (Galectin-3)

Immunogen: Recombinant (partial), amino acids 151-251

Format: Purified

Isotyp: IgG1, kappa chain  (Passende Sekundärantikörper)

Klon: Gal397

Beschreibung: Galectin-3 (galactose-specific lectin 3) is a 30-32 kD glycoprotein, also know as Mac-2, Gal-3, RL-29,galactose-specific lectin 3, CBP-35, L-34, and epsilonBP. It is a member of animal beta-galactoside-binding protein family thatis expressed in cell nucleus, cytoplasm, plasma membrane, or extracellular matrix by variety of tumor cells,monocytes/macrophages, epithelial cells, Kupffer cells, and dendritic cells. Galectin-3contains carbohydraterecognition domains and binds to beta-galactoside residues bearing glycoproteins, such as as IgE, IgA, galactose,casein kinase I, laminin, mucin, LAMPs, and CD66. Galectin-3 is an adhesion molecule and plays an important role inregulation of cell proliferation, differentiation and tumor cell metastasis. Galectin-3 structurely possesses NWGR motifthat is conserved in BH-1 domain of BCL-2 family and functions as an anti-apoptotic molecule.

Anwendungen

Applikationshinweise: Each lot of this antibody is quality control tested by immunoEach lot of this antibody is quality control tested byimmunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of thisreagent is ? 0.25 ug per 106 cells in 100 ul volume. It is recommended that the reagent be titrated for optimalperformance for each application.* Alexa Fluor

Reinigung: The antibody was purified by affinity chromatography.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Lagerung: The antibody solution should be stored undiluted at 4 degrees C.

Beschränkungen: Nur für Forschungszwecke einsetzbar