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Interleukin 12 (IL12) Antikörper
| Antigen | Interleukin 12 (IL12) |
| Synonyme | CLMF, NKSF, CLMF2, NKSF2, IL-12B, IL12A, p40, Il-12b, Il12p40, Il-12p40, Il12, IL12B, IL-12p40, IL-12, il12b, IL-12 p40, MGC152789, il12p40.b, zgc:152789, IL-12.p40, Il12b, LOC100217488 |
| Klonalität | Monoklonal (C18-2) |
| Wirt |
 Alternativen Ratte |
| Reaktivität |
Alternativen Maus |
| Applikation |
Alternativen ELISA (Fangantikörper)
|
| Produktnummer | ABIN313997 |
| Menge | 50 ug (Varianten) |
| Preis | 98,57 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
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| Verfügbarkeit | Lieferung in 5 bis 7 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | IL-12 (p70) |
| Immunogen | CHO expressed, recombinant mouse IL-12 p70 |
| Format | Purified |
| Isotyp | IgG2a, kappa chain (Passende Sekundärantikörper) |
| Klon | C18-2 |
| Beschreibung | Interleukin 12 (IL-12) is a heterodimeric pleiotropic 70 kD (p70) cytokine consisting of a 40 kDa (p40) subunit and a 35kDa (p35) subunit. IL-12 is a potent regulator of cell-mediated immune responses and key mediator of Th1 celldevelopment. Bioactive IL-12 is secreted by activated B lymphocytes, dendritic cells, and macrophages in responseto pathogens or upon interaction with activated T cells. IL-12 p70 stimulates cytotoxic T, NK and LAK cellproliferation, and induces IFN-gamma and TNF production in resting and activated T and NK cells. It has been suggestedthat IL-12 may have therapeutic potential as a vaccine adjuvant that promotes cellular-immunity and as an anti-tumorand anti-viral agent. |
Anwendungen
| Applikationshinweise | Each lot of this antibody is quality control tested by ELISA assay. For use as an ELISA capture antibody, aconcentration range of 1-4 ug/ml is recommended. To obtain a linear standard curve, serial dilutions of IL-12(p70)recombinant protein ranging from 500 to 4 pg/ml are recommended for each ELISA plate. It is recommended that thereagent be titrated for optimal performance for each application. ELISA Capture: The purified C18.2 antibody is useful as a capture antibody for a sandwich ELISA assay, when usedin conjunction with the biotinylated C17.8 antibody as detection antibody and recombinant mouse IL-12 p70 as thestandard. |
| Reinigung | The antibody was purified by affinity chromatography. |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Lagerung | The antibody solution should be stored undiluted at 4 degrees C. |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Alternativen
Alternativen zu Antigen "Interleukin 12 (IL12)", Typ "Antikörper" finden
| Wirte | Maus (35), Ziege (21), Ratte (14), Kaninchen (4) |
| Reaktivitäten | Human (36), Maus (23), Rind (Kuh) (6), Fisch (2), Schwein (2), Katze (1), Hund (1), Ratte (Rattus) (1) |
| Applikationen | ELISA (52), Western Blot (WB) (34), Durchflusszytometrie (FACS) (16), Neutralisierung (Neut) (11), Funktionale Studien (Func) (9), ELISA (Fangantikörper) (4), ELISPOT (2), Immunhistochemie (IHC) (2), ELISPOT (Fangantikörper) (1), Immunfluoreszenz (IF) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1) |
| Konjugate | Biotin (10), PE (3), EFluor 450 (2) |
