Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT) Antikörper

Antigen: Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT)

Synonyme: CRIK, STK21, KIAA0949, CIT, crik, xcit, stk21

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Immunfluoreszenz (IF)

Produktnummer: ABIN313937

Produktbeschreibung

Weitere Bezeichnung: CRIK

Immunogen: Peptide-KLH, C-terminal

Format: Purified

Isotyp: IgG  (Passende Sekundärantikörper)

Klon: Poly6364

Beschreibung: CRIK (Citron Rho-interacting kinase) is a serine/threonine kinase belonging to the myotonic dystrophy kinase family.This kinase contains an AGC-kinase C-terminal domain, CNH domain, PH domain, phorbol-ester/DAG-type zincfinger, and a protein kinase domain. Citron kinase can be produced in at least two different isoforms: CitronRho-interacting kinase (CRIK) and CRIK-short kinase (SK). CRIK is a 231 kD protein in which the kinase domain isfollowed by the sequence of Citron, a previously identified Rho/Rac binding protein. SK is a ~54 kD protein whichconsists mostly of the kinase domain. Citron kinase binds to Rho-GTP and has been shown to be involved in theregulation of cytokinesis, control of G2/M transition in the hepatocyte cell cycle, and the development of the centralnervous system. The Poly6364 antibody recognizes human CRIK and has been shown to be useful forimmunoflorence staining.

Anwendungen

Applikationshinweise: Each lot of this antibody is quality control tested by immunofluorescence staining. For immunofluorescencemicroscopy: Use a dilution range of 1:100~1:400. It is recommended that the reagent be titrated.

Reinigung: This antibody was purified by affinity chromatography.

Buffer: This antibody is provided in phosphate-buffered solution, pH 7.2, containing0.09% sodium azide and 50% glycerol.

Lagerung: Upon receipt, store frozen at -20 degrees C.

Beschränkungen: Nur für Forschungszwecke einsetzbar