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C-Fos Antikörper

Antigen

C-Fos
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen
Reaktivität
Alternativen

Human, Ratte (Rattus), Maus
Applikation
Alternativen Western Blot (WB)
Produktnummer ABIN313930
Menge 100 ul  (Varianten)
Preis 275,71 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 5 bis 7 Werktagen

Produktbeschreibung
Anwendungen Alternativen Sekundärantikörper Varianten zurück nach oben

Immunogen DMDLSGSFYAADWEC (aa. 291-304 of human c-Fos)Reactivity: HumanCross-
Format Purified
Klon Poly6414
Beschreibung The c-fos protein, also known as FBJ murine viral (v-fos) oncogene homolog , is a 62 kD cellular oncogene. The c-fosprotein contains a bZIP region with a DNA-binding domain and a leucine zipper domain. Together with c-jun, c-junproteins form the heterodimeric AP-1 complex that binds to the TRE elements of cellular and viral genes includingcollagenase, interleukin 2, stromelysin, SV40 and polyoma among others. c-fos is expressed in a variety of normaladult tissues and has been implicated as a critical transcription factor for skeletal formation and maintenance. Thistranscription factor is modified by phosphorylation by a number of upstream kinases and has been shown to interactwith a variety of other proteins involved in transcriptional regulation. c-fos has been implicated in the development offibrous bone dysplasia and osteosarcoma. The c-fos protein has been shown to interact with a variety of otherproteins including c-jun, TFIID, NCOA2, NFAT1, CHOP, ELK1, SRC1, and ETS1. The Poly6244 antibody recognizeshuman, rat, and mouse c-fos and has been shown to be useful for Western blotting, immunoprecipitation, andimmunohistochemistry.

Anwendungen
Alternativen Sekundärantikörper Varianten zurück nach oben

Applikationshinweise Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s):Use 10 ul per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimalperformance for each application.
Reinigung The antibody was purified by antigen-affinity chromatography.
Buffer This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 50% glycerol.
Lagerung Upon receipt, store at -20 degrees C.
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen
Anwendungen Sekundärantikörper Varianten zurück nach oben

Alternativen zu Antigen "C-Fos", Typ "Antikörper" finden
Wirte Kaninchen (58), Maus (11), Schaf (11), Huhn (2)
Reaktivitäten Human (66), Ratte (Rattus) (51), Maus (44), Schwein (21), Hund (9), Rind (Kuh) (8), Kaninchen (3), Huhn (2), Hamster (2), Vogel (1), Katze (1), Pferd (1)
Applikationen Western Blot (WB) (55), Immunfluoreszenz (IF) (21), Durchflusszytometrie (FACS) (20), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (13), Enzyme Immunoassay (EIA) (11), Immunhistochemie (Paraffinschnitte) (IHC (p)) (11), ELISA (6), Immunhistochemie (IHC) (5), Immunpräzipitation (IP) (5), Dot Blot (Dot) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Elektromobilitäts-Experimente (EMSA) (1), Funktionale Studien (Func) (1), Immunelektronenmikroskopie (EM) (1)
Konjugate Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitope N-Term (4), pT232 (1), pThr232 (1)