BiP Antikörper

Antigen: BiP

Klonalität: Monoklonal (76-E6)

Wirt: Ratte

Reaktivität: Maus

Applikation: Western Blot (WB)

Produktnummer: ABIN313805

Produktbeschreibung

Immunogen: Mouse BiP:u chain complexes

Format: Purified

Isotyp: IgG2a, kappa  (Passende Sekundärantikörper)

Klon: 76-E6

Beschreibung: Originally identified as an immunoglobulin heavy chain-binding protein in pre-B cells, BiP was found to be involved instress responses and also as a molecular chaperone in intracellular protein transport, prevention of protein toxicityand direction of protein folding and assembly in the endoplasmic reticulum. Because so many ER proteins interacttransiently with BiP, it may play a key role in monitoring protein transport through the cell.

Anwendungen

Applikationshinweise: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is approx. 1.0 ug per 106 cells in 100 ul volume. It isrecommended that the reagent be titrated for optimal performance for each application.

Reinigung: The antibody was purified by affinity chromatography.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Lagerung: The antibody solution should be stored undiluted at 4 degrees C.

Beschränkungen: Nur für Forschungszwecke einsetzbar