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BCL2-Associated X Protein (BAX) Antikörper

Antigen

BCL2-Associated X Protein (BAX)
Synonyme BCL2L4, bax, fj16e01, wu:fc50b10, wu:fj16e01, BAX, bax-A, xBax, xlbax, MGC76049, BAX-ALPHA
Klonalität Monoklonal (2D2)
Wirt
Reaktivität
Alternativen

Human
Applikation
Alternativen Western Blot (WB), Immunpräzipitation (IP), Intrazelluläre Durchflusszytometrie (ICFC), Immunhistochemie (IHC)
Produktnummer ABIN313788
Menge 100 ug  (Varianten)
Preis 227,14 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 5 bis 7 Werktagen

anti-BCL2-Associated X Protein (BAX) antibody

Produktbeschreibung
Anwendungen Bilder Alternativen Sekundärantikörper Varianten zurück nach oben

Weitere Bezeichnung Bax
Immunogen Amino acid: 3-16 of human Bax protein
Format Purified
Isotyp IgG1, kappa chain  (Passende Sekundärantikörper)
Klon 2D2
Beschreibung Bax is a 21 kD pro-apoptotic protein known to regulate apoptosis. Bax is found in the cytoplasm, mitochondria, andnucleus and is highly expressed in hematopoietic stem cells, the ovary, and in the lymph node. Bax binds theanti-apoptotic protein Bcl-2 as a heterodimer or forms homodimers. The relative levels of pro-apoptotic proteins suchas Bax and anti-apoptotic proteins such as Bcl-2 determines whether cell death will occur following an apoptoticstimulus. Bax accelerates the opening of mitochondrial VDAC altering membrane potential and allowing cytochrome cto pass out of the mitochondria into the cytosol to initiate downstream caspase activation. p53 can transcriptionallyactivate the Bax gene to induce apoptosis. Bax has been shown to be mutated in some human cancers. Clone 2D2 has been shown to be useful for western blotting, immunoprecipitation, immunofluorescence andimmunohistochemistry of the human Bax protein. This antibody does not cross-react with Bcl-2 or Bcl-XL proteins.

Anwendungen
Bilder Alternativen Sekundärantikörper Varianten zurück nach oben

Applikationshinweise Each lot of this antibody is quality control tested by Western blotting. ForWestern blotting, suggested working dilution(s): Use 5 ug per 5 ml antibodydilution buffer for each mini-gel. It is recommended that the reagent betitrated for optimal performance for each application.
Reinigung This antibody was purified by affinity chromatography.
Buffer This antibody is provided in phosphate-buffered solution, pH 7.2, containing0.09% sodium azide at 0.5 mg/ml.
Lagerung Upon receipt, store undiluted at 4 degrees C.
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen
Anwendungen Bilder Sekundärantikörper Varianten zurück nach oben

Alternativen zu Antigen "BCL2-Associated X Protein (BAX)", Typ "Antikörper" finden
Wirte Maus (103), Kaninchen (89), Schaf (3)
Reaktivitäten Human (167), Maus (98), Ratte (Rattus) (91), Hund (33), Rind (Kuh) (32), Schwein (31), Schaf (30), Affe (3), Huhn (1), Pferd (1), Kaninchen (1)
Applikationen Western Blot (WB) (131), Immunfluoreszenz (IF) (76), Immunpräzipitation (IP) (61), Immunhistochemie (Paraffinschnitte) (IHC (p)) (49), Durchflusszytometrie (FACS) (38), ELISA (18), Immunhistochemie (IHC) (16), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (15), Enzyme Immunoassay (EIA) (12), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (4), Dot Blot (Dot) (2), Immunoelectron Microscopy (IEM) (2), Intrazelluläre Durchflusszytometrie (ICFC) (1)
Konjugate Biotin (8), Alexa Flour 488 (2), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), FITC (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2), RBITC (2)
Epitope N-Term (3), universal (1)