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Antikörper
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anti-Adducin 1 (Alpha) (ADD1) (Thr455) Antikörper
Adducin 1 (Alpha) (ADD1) (Thr455) Antikörper
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| Synonyme |
ADDA, MGC3339, MGC44427, AI256389, MGC124621, ADD1, cb787, bZ1H20.1, MGC158352, zgc:158352, DKFZp459A0431, add1-a, add2, adda, MGC69376 |
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Epitope
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| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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| Produktnummer |
ABIN313775 |
| Menge |
25 ul (Varianten) |
| Preis |
104,29 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 5 bis 7 Werktagen |
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Weitere Bezeichnung
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alpha-Adducin-Phosphorylated (Thr455)
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Immunogen
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Peptide-KLH
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Format
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Purified
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Isotyp
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IgG (Passende Sekundärantikörper)
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Klon
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Poly6321
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Beschreibung
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The alpha-adducin protein is a ubiquitously expressed cytoskeletal protein thatbinds with high affinity to Ca2+/calmodulin and acts as a substrate for proteinkinases A and C. alpha-addducin is a 80-120 kD member of the aldolase class IIfamily and adducin subfamily. This protein has three isoforms that interact asheterodimers alpha/beta, and alpha/gamma. The molecular weights for the various isoforms arealpha=120 kD, beta=110kD, gamma=80kD. This protein has been reported to promote theassembly of the spectrin-actin network. Polymorphisms in alpha-adducin areassociated with cardiovascular disease and hypertension. alpha-adducin hasbeen reported to interact with calmodulin. When phosphorylated byRho-kinase, alpha-adducin can regulate membrane ruffling and cell motility. ThePoly6321 antibody has been shown to be useful for immunofluorescencemicroscopy of mouse and human alpha-adducin protein.
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Applikationshinweise
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Each lot of this antibody is quality control tested by immunofluorescencestaining. For immunofluorescence microscopy: Use a dilution range of1:100~1:400. It is recommended that the reagent be titrated for optimalperformance for each application.
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Reinigung
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The antibody was purified by antigen-affinity chromatography.
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Buffer
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This antibody is provided in phosphate-buffered solution, pH 7.2, containing0.09% sodium azide and 50% glycerol.
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Lagerung
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Upon receipt, store frozen at -20 degrees C.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Adducin 1 (Alpha) (ADD1)", Typ "Antikörper" finden
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Wirte
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Kaninchen (43), Maus (3)
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Reaktivitäten
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Human (46), Maus (36), Ratte (Rattus) (30), Huhn (1), Xenopus laevis (1)
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Applikationen
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Western Blot (WB) (42), Immunfluoreszenz (IF) (27), Immunhistochemie (IHC) (17), Immunhistochemie (Paraffinschnitte) (IHC (p)) (14), Enzyme Immunoassay (EIA) (6), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (6), Immunpräzipitation (IP) (6), ELISA (5), Dot Blot (Dot) (1), ELISA (Detektionsantikörper) (1)
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Epitope
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pSer726 (8), Ab-726 (5), C-Term (1), Thr455 (1), pSer481 (1), pSer59 (1), pThr445 (1)
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Alternativen 
